About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: Quinazolinone is a heterocyclic compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the 4-isomer being the more common. Various novel classes of structurally different quinazolinones have been designed and synthesized depicting potential interventions such as antibacterial, antifungal, antiviral, anticonvulsant, CNS depressant, anti-inflammatory, ... Read More »
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Category Archives: Pharmaceutical Chemistry and New drug design
SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF 4-[2′-(5′-NITRO) IMIDAZOLYL] BENZOYL(N-Me) AMINO ACID DERIVATIVES
About author : Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: A great number of drugs are heterocyclic compounds, mostly are of synthetic origin, few have obtained from natural resources which include alkaloids, xanthines, cardiac glycosides, vitamins and several antibiotics. Heterocyclic derivatives having two nitrogen atoms oriented in, 1-3 position are endowed with wide spectrum of ... Read More »
Synthesis and characterization of 3-((5-phenyl-1, 3, 4-oxadiazol-2-yl)Methyl amino)-2-methyl quinazolin-4(3H)-one
About author : Ramesh Dhani JNTUA – OTRI, Anantapur, India Dept.of Pharmaceutical Chemistry E-mail: [email protected] ABSTRACT: Quinazolinone is a heterocyclic chemical compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the 4-isomer being the more common. Various novel classes of structurally different quinazolinones have been designed and synthesized depicting potential interventions such as antibacterial, antifungal, antiviral, anticonvulsant, CNS depressant, ... Read More »
SYNTHESIS AND PHYSICO-CHEMICAL ANALYSIS OF 2-SUBSTITUTED BENZOXAZOL – 5-CARBOXYLIC ACID ARYLIDENE HYDRAZIDES
About author : Ramesh Dhani JNTUA-OTRI, Anantapur, India Dept. of Pharmaceutical Chemistry E-mail: [email protected] ABSTRACT: Oxazole is the parent compound for a vast class of heterocyclic aromatic organic compounds. These are azoles with oxygen and nitrogen separated by one carbon. Oxazoles are aromatic compounds but less so than the thiazoles. Oxazole is a weak base; its conjugate acid has a ... Read More »
SYNTHESIS AND CHARACTERIZATION OF 3-[(5-(4-CHLOROPHENYL) 1, 3, 4-OXADIAZOL-2-YL) METHYL AMINO]-2-METHYL QUINAZOLIN-4(3H)-ONE
About author : Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: Quinazolinone is a heterocyclic chemical compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the 4-isomer being the more common. Various novel classes of structurally different quinazolinones have been designed and synthesized depicting potential interventions such as antibacterial, antifungal, antiviral, anticonvulsant, CNS ... Read More »
SYNTHESIS AND CHARACTERIZATION OF ETHYL (1H-BENZIMIDAZOL-2-YL- SULFANYL) ACETATE
About author: Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, anantapur, India E-mail: [email protected] ABSTRACT: The benzimidazole contains a phenyl ring fused to an imidazole ring, as indicated in the structure of benzimidazole. Recently in benzimidazole chemistry has been revived somewhat by the discovery that the 5, 6-dimethyl benzimidazole moiety is a part of the chemical structure of vitamin B12. Diversity ... Read More »
Synthesis and Characterization of 2-[1H-benzimidazole-2yl-sulfanyl]-N-[(E)-(3-methylphenyl) methylidene] acetohydrazide
About author Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: Many important biochemical compounds and drugs of natural origin contain heterocyclic ring structures. Among these e.g. Carbohydrates, essential amino acids, vitamins, alkaloids, glycosides etc. the presence of heterocyclic structures in such diverse types of compounds is strongly indicative of the diverse types of the pharmacological activity. ... Read More »