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About author : Ankit Agarwal*, Subhash Dadhich, Sunil Kumar Tiwari, Kashyap Nagariya R & D Division, Ahlcon Parenterals (I) Ltd., Bhiwadi, Rajasthan, India *e-mail: ankitagarwal005@gmail.com ABSTRACT : To develop a simple, rapid and accurate HPLC method for simultaneous quantitative determination of Dexamethasone and Gatifloxacin in ophthalmic solution. Chromatographic separation was achieved with PDA detector using Inertsil C18, 250 x 4.6mm, ... Read More »

About author : Jony Mallik* Department of Pharmacy, Southern University Bangladesh, Chittagong-4200. *e-mail: jonypharmapub@gmail.com INTRODUCTION Pharmaceutical analysis has greatest importance in pharmaceutical science, specially in terms of Research & Development (R&D), Drug-Product design, Quality Control Department of a Pharmaceutical Industry. Among the number of spectroscopic analytical techniques, Mass Spectrometry occupied a large area of whole analytical zone. The very important ... Read More »

About author: Chinmaya Keshari Sahoo* Research Scholar,Dept. of Pharmaceutics, OUCT, Osmania University,A.P, India *e-mail: sahoo.chinmaya83@gmail.com INTRODUCTION : Analytical method validation is a regulatory requirement that refers to the evaluation and proving that the selected analytical method shall ensure reproducible and reliable results adequate for the intended purpose.The process of analytical method validation should demonstrate that the method is fit for ... Read More »

About author : Anup K. Chakraborty*, Umesh K. Patil Dept of Pharmaceutical Chemistry, School of Pharmacy & Research Centre, People’s University, Bhopal (M.P.), India *e-mail: anup.ckbty@yahoo.co.in Abstract: Incretin hormones are defined as intestinal hormones released in response to nutrient ingestion, which potentiate the glucose-induced insulin response. In humans, the incretin effect is mainly caused by two peptide hormones, glucose-dependent insulin ... Read More »

About author : Praveena S*, Dr. Hindustan Abdul Ahad Dept.  of Pharmaceutical analysis, Balaji College of Pharmacy, AP, India *e-mail: veenajessica@gmail.com INTRODUCTION Iron is essential for life. Not only it is found in proteins and enzymes, but it is responsible for cell growth and transporting oxygen throughout the body. Excessive or insufficient amounts however, may result in serious health issues. ... Read More »

About author: P. Sudheer Kumar Narayana Pharmacy College, A.P, India E-mail: psudhir11@gmail.com ABSTRACT: Chalcone is an aromatic ketone that forms the central core for the variety of important biological compounds, which are collectively known as chalcones. The name chalcones was given by Kostanecki and Tambor. The chalcones, two aromatic rings are linked by an aliphatic three carbon chain which bears ... Read More »

About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA – OTRI, India E-mail : dhanipharmachem@gmail.com Abstract: Recently in benzimidazole chemistry has been revived somewhat by the discovery that the 5,6-dimethyl benzimidazole moiety is a part of the chemical structure of vitamin B12.The benzimidazoles are also known as benziminazolones or benzoglyoxalines.The new benzimidazole derivative i.e, 2-mercapto benzimidazole was synthesized.The melting point ... Read More »

About author : P. Sudheer Kumar Narayana Pharmacy College, A.P, India. E-mail: psudhir11@gmail.com ABSTRACT: Chalcone is an aromatic ketone that forms the central core for the variety of important biological compounds, which are collectively known as chalcones. The derivatives of chalcones with an annular nitrogen atom in the phenyl ring were reported to have a wide range of biologically activities, ... Read More »

About author: P. Deepthi Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur,India E-mail: deepthi.pharma07@gmail.com INTRODUCTION :A natural product is a chemical compound  or substance produced by a living organism – found in nature that usually has a pharmacological or biological activity for use in pharmaceutical drug discovery, drug design. A natural product can be considered as such even if it ... Read More »

About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA-OTRI, India E-mail: dhanipharmachem@gmail.com ABSTRACT: Introduction of D-amino acids and N-methylation of amino acids like tyrosine, valine, alanine etc enhanced antimicrobial activity. Condensation of heterocyclic moieties viz nicotinic acid, thiazole, coumarin, quinoline, furan, imidazole etc. with amino acids and peptides resulted in compounds with potent biological activities. Many of the heterocyclic found ... Read More »