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Sreedevi Adikay*, Sumalatha Jorepalli, Prasanthi Doppalapudi Division of Pharmaceutical Chemistry, Institute of Pharmaceutical Technology, Sri Padmavati Mahila Visvavidyalayam, Tirupati-517502, A.P, India A B S T R A C T Obesity is of public health concern because of its association with medical complications that lead to increased morbidity and mortality. From time immemorial, traditional medicinal plants had gained importance in modulating ... Read More »
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Category Archives: Chemical Sciences and Chemical research
Identification of Gene and evaluation of biological activities in berries of Solanum nigrum (Linn.)–a medicinal plant of North India
Chandan Prasad1, Vimal Kumar*, 2, S.K. Srivastava1, Sanjay Asthana1, Kamal Kumar3, Ashok Naglot4, R.B. Srivastava5 1Department of Chemistry, D.A.V. P.G. College, Kanpur -208001, Uttar Pradesh, India. 2Science Laboratory, Archaeological Survey of India, Dehradun-248001, Uttrakhand, India. 3Defence Materials and Stores Research and Development Establishment, Kanpur- 208013, Uttar Pradesh, India. 4Defence Research Laboratory, Post Bag 2, Tezpur-784001, Assam, India. 5Defence Institute of High ... Read More »
Study on In-vitro Antioxidant Potential of Solanum Incanum Fruit Extract
T. Indhumathi*1, Dr. S. Suja2 1PG and Research Department of Biochemistry, Dr. N.G.P Arts and Science College, Coimbatore-48, India 2PG and Research Department of Biochemistry, P.S.G College of Arts and Science, Coimbatore -14, India A B S T R A C T Ethanolic extract of Solanum incanum fruit were tested for in-vitro free radical scavenging assays, such as hydroxyl radical, ... Read More »
Cycloaddition involving activated isothiocyanate: Synthesis and antimicrobial activities of thiazine, pyrimidine and pyridine derivatives
Amira A.Ghoneim*, Mohamed G.Assy, Enaiat K.Mohamed, Islam Ragab Chemistry Department, Faculty of Science, Zagazig University, Zagazig, Egypt A B S T R A C T Aniline was added to acylisothiocyante [1] to produce 1,3-thiourea derivative [2]. Allowing compound [2] to react with sodium ethoxide, at room temperature resulted in thiazine cyclization affofding [3]. Refluxing 2 in sodium ethoxide afforded the ... Read More »
Synthesis and Characterization of Silver Nanoparticles Using Basella Rubra Linn and their In-vitro Cytotoxic Studies
Rajathi.K1, S.Suja2 & N.Kannikaparameswari3 1Assistant professor, PG and Research Dept. of Biochemistry, Dr. N.G.P Arts and Science College, Kalapatti road, Coimbatore-48. 2Assistant Professor, PG and Research Department of Biochemistry, P.S.G College of Arts and Science, Coimbatore 3Associate Professor, PG and Research Department of Biochemistry, Dr. N.G.P Arts and Science College, Kalapatti road, Coimbatore-48. A B S T R A C ... Read More »
Synthesis and application of Schiff base in resolution-racemization of primary amines
P. Venkateswara Rao1, A.V.G.S. Prasad*1,P.S.S. Prasad*2 1Department of Chemistry, Nizam College (Autonomous), Hyderabad, Andhra Pradesh, India. 2Drug Control Administration, Hyderabad, India. A B S T R A C T In the past decade there has been a significant growth in the sales of pharmaceutical drugs worldwide, but more importantly there has been a dramatic growth in the sales of single ... Read More »
Azetidinone-as a Core Biological evaluation Agent- A Review
S. Murali Krishna, Y. Padmalatha, L.K. Ravindranath Department of Chemistry, S.K. University, Anantapur-515003,A.P, India A B S T R A C T The article is aimed to discuss characterize and screening the biological activity of a series of Azetidinone as a Core Biological evaluation Agent. Azetidinones are of great biological interest, especially as anti-tubercular antibacterial. The important and structural diversity ... Read More »
Analytical Method Development and Validation of Simultaneous Estimation of Tramadol, Paracetamol, Domperidone in Tablet Dosage Form by RP-HPLC
Nagaraju.Y*, A. Ajitha and Uma Maheshwar Rao. V Departmentof Pharmaceutical Analysis, CMR College of Pharmacy, Ranga Reddy-501401, India A B S T R A C T A simple reverse phase high pressure liquid chromatography (RP-HPLC) method has been developed and validated for simultaneous estimation of tramadol paracetamol and domperidone in tablet dosage forms. The compounds were separated on inertsil C-18 ... Read More »
Molecular Properties and Bio-Activity Score of Alkaloids in Erythna Varigata Leaves to find Lead Compound
Dr (Mrs). G.Valli*2 and A. Jayalakshmi1 1Department of Chemistry, S.F.R. College, Sivakasi, Tamilnadu, India 2Associate Professor & Head, Department of chemistry, S.F.R. College, Sivakasi, Tamilnadu, India A B S T R A C T Molecular properties and Bio-Activity score of alkaloids present in erythrina varigata leaves were calculated using molinspiration software. MiLog P values of these compounds were found to ... Read More »
One Pot Synthesis and Biological Activities of Schiff Base
P. Venkateswara Rao, A.V. G.S. Prasad*1, P.S.S. Prasad *2 1Department of Chemistry, Nizam College (Autonomous), Hyderabad, Telangana, India. 2Drug Control Administration, Hyderabad, Telangana, India. A B S T R A C T In the present study an intermolecular reductive Schiff base formation from nitroarene and benzaldehyde to yield diarylimine is carried out in the presence of iron powder and ammonium ... Read More »
