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Ganesh S. Kulkarni, Priyanka L. Anandgaonker, Sidharth D. Janrao, Digambar D. Gaikwad and D. M. Janrao* 1Department of chemistry J.E.S. College Jalna-431203 2Deptment of Chemistry, Govt. College of Arts & Science, Aurangabad-431001 A B S T R A C T Hydrazones possessing an azometine -NHN=CH– proton constitute an important class of compounds for new drug development. In the present protocol ... Read More »
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Category Archives: Chemical Sciences and Chemical research
Biochemical Evaluation of Some Medicinal Plants of Genus Terminalia (Combretaceae) of Marathwada Region in Maharashtra
Kadam V.B*1, Salve S.B1, Deore S.V1, Patil Vikas2, Khandare K.R3 1P. G. Department of Botany & Research Centre, K. T. H. M. College, Nasik, India-422002 2Dy. Registrar, Savitribai Phule Pune University, Pune, India 3Department of Botany, Arts, Commerce and Science College, Satana, Nashik, India A B S T R A C T The seasonal variation of total ash, acid soluble ... Read More »
Method Development and Validation for Simultaneous Determination a Multiple Drug Dosage Form of Paracetamol, Phenylepherine and Caffeine by RP-HPLC
Dr. Samson Israel Deta*1, Dr. Kommana Balaram Kumar2, Hayelom G/Kirstos Mangesha3 1Asst. Prof, Adigrat University, Ethiopia 2Asst.Prof, University of Gondar, Ethiopia 3Lecturer, Adigrat University, Ethiopia A B S T R A C T This method describes a procedure to quantify the assay of Paracetamol, Phenylepherine and caffeine tablet using a mobile phase containing containing mixture of 880 mL of sodium ... Read More »
Evaluation of an Expired Non-Toxic Amlodipine Besylate Drug as Corrosion Inhibitor for Low Carbon Steel in Hydrochloric Acid Solutions
A.S. Fouda*1, M. S. Motawee2, H. S. Megahid2, H. A. Abdul Mageed1 Chemistry Department, Faculty of Science, Mansoura University, Mansoura-35516, Egypt. A B S T R A C T Inhibition of low carbon steel corrosion by Amlodipine Besylate in 1M HCl was investigated by weight loss, potentiodynamic polarization, electrochemical impedance spectroscopy (EIS) & electrochemical frequency modulation (EFM) measurements. The inhibition ... Read More »
Synthesis and Screening of (E)-1-(4-(2(((Phenylamino) Methyl) amino) acetyl) phenyl)-4-(2-phenylhydrazono)-3-(Trichloromethyl)-1H-pyrazol-5(4H)-one
G.S.S. Anjaneya Vasavi, M. Uma Maheshwar Rao, S. Sreenivasulu*, M. Venu Gopal Department of Chemistry, R.G.M. College of Engineering Technology (Autonomous) Nandyala A B S T R A C T Synthesis of (E)-1-(4-(2-(((phenylamino) methyl) amino) acetyl) phenyl)-4-(2phenyl hydrazono)-3-(trichloromethyl)-1H-pyrazol-5(4H)-onewasachievedbyreactionofE-2-(4-(5-o4(2phenylhydrazono)-3-(trichloromethyl acetic acid (2)) in presence of DMF, aq NaNO3, isobutyl formamide afforded corresponding compound (3) which was subjected to mannich reaction ... Read More »
Synthesis, Characterization and In-vitro evaluation of Antibacterial Profile of 1, 4-dihydropyridine derivatives
Asish Bhaumik1*, Prasenjit Das2, Shibu Das3, M. Swapna4, Mahendar Boddupally5 1,4Department of Pharmaceutical Chemistry, Teja College of Pharmacy, Kodad, Nalgonda-508206, Telangana State, India. 2,3Department of Pharmaceutical Chemistry, Regional Institute of Pharmaceutical Science and Technology, Abhoynagar, Agartala-799005, India 5Department of Pharmacology, Pratishta Institute of Pharmaceutical Sciences, Durajpally, Chivemla, Nalgonda-508214, Telangana State, India. A B S T R A C T The ... Read More »
Co-ordination Polymers of Schiff Bases and Their Applications: A Review
J. B. Devhade* P. G. Department of Chemistry, Jijamata Mahavidyalaya Buldana, Maharashtra– 443001, India Abstract The condensation of primary amines with carbonyl compounds was first reported by Schiff and condensation products often referred as Schiff bases. These bases have general structure RC=NR’ where R and R’ are alkyl, cyclohexyl, aryl or heterocyclic radicals which may be differently substituted. Schiff bases ... Read More »
A Novel Method for the Simultaneous Estimation of Imipenem and Cilastatin by Using RP-HPLC in its Bulk and Pharmaceutical Dosage Form
Satheesh thotla*, R. Vasanthi, Dr. Alagar Raja.M, K.N.V Rao, Devid Banji Departmernt of Pharmaceutical Analysis, Nalanda College of Pharmacy, Nalgonda, Telangana, India A B S T R A C T A new method was established for simultaneous estimation of Imipenem and cilastatin by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Imipenem and cilastatin by using ... Read More »
The Evaluation of Combine Drug Action of Codeine as Supplementary Drug with Dakin-West β-Acetamidoketones
Deepak. M. Nagrik* Department of Chemistry, G.S. Science, Arts and Commerce College, Khamgaon-444303, M.S., India A B S T R A C T β-acetamido ketones were synthesized in high yields under mild condition via four component Dakin-West reaction which carried out by condensation of aromatic aldehydes, enolizable ketones, acetonitrile and acetyl chloride in presence of mixed metal oxide CuO-SnO2 as ... Read More »
The Fruit of Punica granatum act as Potential Cytotoxic agent against the human breast cancer cell line HS-578T
Asish Bhaumik1*, K. Narender Naidu2, Mahendar Boddupally3, Md. Salmasultana4 1, 4Department of Pharmaceutical Chemistry and Analysis, Teja College of Pharmacy, Kodad, Nalgonda-508206, Telangana, India. 2Department of Pharmaceutics, MITS College of Pharmacy, Kodad, Nalgonda-508206, Telangana, India. 3Department of Pharmacology, Pratishta Institute of Pharmaceutical Sciences, Durajpally, Chivemla, Nalgonda-508214, Telangana, India. A B S T R A C T The edible fruit of Punica ... Read More »
