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Mulla Rafiyuddin*, Akepogu Jayaraju, J. Sreeramulu Department of Chemistry, Sri Krishnadevaraya University, Anantapuramu–515003, Andhra Pradesh, India A B S T R A C T A reverse phase high performance liquid chromatographic method was developed for the determination of Gemcitabine and Clarithromycin in bulk and pharmaceutical dosage form. The separation was carried out on a [Column: Agilent C18 (4.6 x 250mm, ... Read More »
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Category Archives: Chemical Sciences and Chemical research
Analytical Method Development and Validation by RP-HPLC for Simultaneous Estimation of Esomeprazole and Levosulpiride in Combined Capsule Dosage Form
V. Amaravathi*, Ramesh Dhani, V. Haribaskar, M. Gobinath, M. Shirisha Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the esomeprazole and levosulpiride in Capsule dosage form. Chromatogram was run through ODS (150mm 4.6mm, 5µ). ... Read More »
A Validated RP-HPLC method for Simultaneous Estimation of Gemcitabine and Clarithromycin in Bulk and Pharmaceutical Dosage form
SK. Kowsar*, V. Hari Baskar, M. Gobinath, Ramesh Dhani, V. Pavan Kumar, K. Giridhar Reddy Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur (M), Nellore, A.P, India. A B S T R A C T A simple, accurate and reproducible RP-HPLC method has been developed for simultaneous estimation of Abacavir and Lamivudine in bulk and tablet dosage form. ... Read More »
Analytical Method Development and Validation by RP-HPLC for Simultaneous Estimation of Moxifloxacin and Prednisolone in Bulk Drug and Pharmaceutical Dosage
K. Kalyani2, P. Sowjanya3, Dr. T. Rajesh4, Dr. Gampa Vijaya Kumar*1 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy. 2,3,4Deapartment of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy. A B S T R A C T A simple, specific, and fast stability indicating reverse phase liquid chromatographic method was established ... Read More »
Method Development and Validation for Simultaneous Estimation of Propranolol and Valsartan by using RP-HPLC in Bulk and Pharmaceutical Dosage Form.
V. Bhargavi2, P. Sowjanya3, Dr. T. Rajesh4, Dr. Gampa Vijaya Kumar*1 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy. 2,3,4Deapartment of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy. A B S T R A C T A simple, sensitive and precise reverse phase high performance liquid chromatographic method has been ... Read More »
Analytical Method Development and Validation by RP-HPLC for Simultaneous Estimation of Metformin Hcl and Vidagliptine in Combined Tablet Dosage Form
V. Geetha2, P. Sowjanya3, Dr. T. Rajesh4, Dr. Gampa Vijaya Kumar*1 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy. 2,3,4Deapartment of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy. A B S T R A C T A simple reverse phase liquid chromatographic method has been developed and subsequently validated for simultaneous ... Read More »
Quinazoline Derivatives and its Biological Significance–A Review
V. Prabhakar*1, K. Sudhakar Babu1, L.K. Ravindranath1, J. Latha3, K. Hari Nagamaddaiah2 1, 2Department of Chemistry, Sri Krishnadevaraya University, Anantapuramu, Andhra Pradesh, India. 3Department of Bio-technology, Sri Krishnadevaraya University College of Engineering and Technology, S.K. University, Anantapuramu–515003, Andhra Pradesh, India. A B S T R A C T Medicinal chemistry is concerned with discovery, development, synthesis in laboratory, thousands of ... Read More »
Synthesis, Characterisation and Biological Evaluation of Novel 1,2,4 Oxadiazole Derivatives
Dr. P. Thriveni, M. Hari Krishna*, K. Murali Department of Chemistry, Vikrama Simhapuri University, Nellore-524003, A.P, India. A B S T R A C T A series of 1,2,4 Oxa di azole derivatives5 (a-g) were prepared by reaction of P-Substituted Aldehydes(4) with hydroxyl amine hydro chloride in NMP & CDI ,DBU to get target compounds. The Structures of the Compounds ... Read More »
Synthesis, Characterisation and Biological Evaluation of Novel Di substituted Quinazoline Linked with Cis Substituted Thio morpholine and 1, 2, 4 Triazole Moieties
V. Prabhakar*1, K. Sudhakar Babu1, L.K. Ravindranath1, J. Latha2 1Department of Chemistry, Sri Krishnadevaraya University, Anantapuramu, Andhra Pradesh, India. 2Department of Bio-technology, Sri Krishnadevaraya University College of Engineering & Technology, S.K. University, Anantapuramu–515003, Andhra Pradesh, India. A B S T R A C T A series of Quinazoline derivatives11 (a-f) were prepared by Nucleophilic substitution reaction of 2,4 di chloro ... Read More »
Synthesis and pharmacological evaluation of 6-sulphnamido cinnoline for Pharmacological and antibacterial activity
Anurag Singh*1, Dr. LVG Nargund2 1Research scholar, CU Shah University, Wardhman City, Gujrat 2Director and Principal, Nargund College of Pharmacy, Bangalore, Karnataka A B S T R A C T Drug discovery, synthesis and development multidisciplinary, creative, complex and highly regulated process Heterocyclic compound are organic compound containing oxygen, sulphur and nitrogen. New drug synthesis not only done loping new ... Read More »
