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V. Prabhakar*1, C. Divya Vani2, B. Roopa2 1Department of Chemistry, Sri Krishnadevaraya University, Ananthapuramu, Andhra Pradesh, India. 2Department of Chemistry, Sri Padmavati Women’s Degree & PG College, Tirupati, Andhra Pradesh, India. A B S T R A C T Heterocyclic compounds occur widely in nature and quite a few of these are essential to life processes. The literature on heterocyclic ... Read More »
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Category Archives: Chemical Sciences and Chemical research
GC-MS Studies of Crinum defixum Ker-Gawler Leaves
A. Elaiyaraja*, G. Chandramohan Department of Chemistry, A.V.V.M. Sri Pushpam College, Poondi, Thanjavur-613 503, Tamilnadu, India. A B S T R A C T The present study was carried out to identify the phytochemical present in the Crinum defixum Ker-Gawler leaves. It is an important medicinal plant worldwide trends towards the utilization of natural plant remedies has created an enormous ... Read More »
Multi-component, Catalyst free Synthesis of α-Aminonitrile by Using of Glycerol as Recyclable and Green Solvent
Amir Hossein zamania*, Saeedeh shariatib, Hamid Reza Ghaienia aMalekAshtar University of Technology, Tehran, Iran, 1465943681 bAhvaz Jundishapur University of Medical Sciences. School of Pharmacy, Ahvaz, Iran, 1579461357 A B S T R A C T We describe the use of glycerol as an efficient, safe and recyclable solvent in the one-pot reaction of aldehydes, amines, and trimethyl silylcyanide to afford ... Read More »
Formulation and Evaluation of Chlorzoxazone Mucoadhesive Tablets
Ch. Praveen Kumar, G. Padmaleela*, S. Sucharitha, K. Gnanaprakash Department of Pharmaceutics, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore-524346, Andhra Pradesh A B S T R A C T In the last two decades, mucoadhesion has shown renewed interest for prolonging the residence time of mucoadhesive dosage forms through various mucosal routes in drug delivery applications. In the present exploration ... Read More »
Structure -Activity Correlation of Thiophene-2- Sulfonic Acid and Thiophene by Rapid Chlorination Kinetics using Hydrodynamic Voltammetry
V.T. Borkar* Department of Chemistry, Nowrosjee Wadia College Research Centre, Affiliated to the Savitribai Phule Pune University, Pune, Maharashtra, India A B S T R A C T The rapid chlorination kinetics of thiophene-2-sulfonic acid by molecular chlorine in aqueous solution has been investigated employing hydrodynamic volatammetry. The specific reaction rate and energy of activation for the reaction were found ... Read More »
Synthesis, characterization and antimicrobial evaluation of novel compounds of 1-(2, 5-difluorobenzoyl)-4-(2-(4-phenyl)hydrazono)-3-(5-(4-(trifluoro methyl) phenyl) -1H-tetrazol-1-yl)-1H-pyrazo l – 5(4H)-one
M. Swarna Kumari*1, K. Sudhakar Babu1, L.K. Ravindhranath1, J. Latha3, K. Harinagamaddaih2 1,2Department of Chemistry, Sri Krishnadevaraya University, Anantapur , A.P, India. 3Department of Bio-technology, SKUCET, Sri Krishnadevaraya University, Anantapur, A.P, India. A B S T R A C T New novel derivatives of 3-chloro-6-(2,5-difluorobenzoyl)-1-(phenylamino) -8-(5-(4-(trifluoromethyl) phenyl)-1H-tetrazol-1-yl)-1,6,7-triazaspiro[3.4]oct-7-ene-2,5-dione (2a-g) were prepared by condensation of 1-(2,5-difluorobenzoyl)-4-(2-phenyl hydrazono)-3-(5-(4-(trifluoromethyl)phenyl)-1H-tetrazol-1-yl)-1H-pyrazol-5(4H)-one(1a-g). Newly synthesized compounds were characterized by ... Read More »
Synthesis of Some New Aminothiophene, Pyridazine, Pyrimidine and Thienopyrimidine Derivatives with expected biological activity
Ismail. M. M. Othman* Chemistry Department, Faculty of Science, Al-Azhar University, Assiut 71524, Egypt. A B S T R A C T Treatment of 1 with active methylene reagents 2a, b and elemental sulfur furnished aminothiophene derivatives 3a, b. diazotization of 3a with active methylene compounds, namely malononitrile (5a) and acetylacetone (5b) afforded the corresponding hydrazono derivatives 6a, b. pyridazine ... Read More »
Synthesis and Characterization of α-Fe2O3 nanoparticles through a Sol- gel approach using carboxylic acid
Ahlam.M.Farhan*1, Hussein .I.Abdulla2, Asmaa.J.Ali3 1Chemistry Department, College of Science for Women, Baghdad University,Iraq 2Chemistry Department, College of Science, AL-Mustansyriah University, Iraq 3Chemistry Department, college of science for women, Baghdad University,Iraq A B S T R A C T Uniform α- Fe2O3 nanoparticles have been prepared by sol- gel method using carboxylic acid maleic acid as chelating agent the structure and ... Read More »
Analytical Method Development and Validation by RP-HPLC for Simultaneous Estimation of Fluoxetine Hcl and Olanzapine in Combined Tablet Dosage Form
SK. Shahina*, M. Gobinath, V. Haribaskar, Ramesh Dhani Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur (M), Nellore, A.P, India. A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Fluoxetine Hcl and Olanzapine in Tablet dosage form. Chromatogram was run through Inertsil C18 ODS column (250mm ... Read More »
Development of a new UV/Visible Spectophotometric and HPLC methods for simultaneous estimation of Metformin and Sitagliptin
Md. Salmasultana1, Asish Bhaumik*2, Hiroshima Kumari3, P. Lavanya4, A. Uma5, T. Haritha6 1,3,4Department of Pharmaceutical Analysis, Teja College of Pharmacy, Kodad, Nalgonda-508206, Telangana, India. 2,5,6Department of Pharmaceutical Chemistry, Teja College of Pharmacy, Kodad, Nalgonda-508206, Telangana, India. A B S T R A C T The main aim and objective of the present research work was to develop a new UV/VISIBLE ... Read More »
