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Category Archives: Chemical Sciences and Chemical research

journal of medicinal chemistry,bioorganic and medicinal chemistry letters,medicinal chemistry research,medicinal chemistry book

Development and Validation for the Extractive Colorimetric Methods for the Determination of Sumatriptan Succinate in Bulk and its Tablet Dosage Form

T. Nuzhath*, S. Muneer, B. Mohammed Ishaq, Dr. Hindustan Abdul Ahad, B. Famida, S. Parveen Department of Pharmaceutical Analysis, Balaji College of Pharmacy, Rudrampeta Bypass, Anantapur– 515001, AP, India A B S T R A C T Two simple, rapid, accurate, precise and economic spectrophotometric methods have been developed for the estimation of Sumatriptan Succinate in pharmaceutical formulation. These methods are ... Read More »

Analytical Method Development and Validation for Determination of Sumatriptan Succinate in Bulk and Its Pharmaceutical Formulation Using UV-Spectrophotometer

T. Nuzhath*, S. Muneer, B. Mohammed Ishaq, Dr. Hindustan Abdul Ahad, B. Famida, S. Parveen Department of Pharmaceutical Analysis, Balaji College of Pharmacy, Rudrampeta Bypass, Anantapur– 515001, AP, India A B S T R A C T A simple UV spectroscopic method was developed and validated for the estimation of Sumatriptan succinate in bulk and pharmaceutical dosage form using distilled water ... Read More »

A Simple UV Spectroscopic Method for the Determination of Tramadol HCl in Bulk and It’s Dosage Form

B. Famida*, S. Muneer, B. Mohammed Ishaq, Hindustan Abdul Ahad, T. Nuzhath PG Department of Pharmaceutical Analysis, Balaji College of pharmacy, Ananthapuramu, Andhra Pradesh, India A B S T R A C T Tramadol hydrochloride (TDL), is chemically [2-(dimethyl amino methyl)-1-(3-methoxyphenyl) cyclohexanol]. [1] It is a centrally acting analgesic, used for treating moderate to severepain, possesses agonist actions at the ... Read More »

Analytical Method Development and Validation by RP-HPLC for Simultaneous Estimation of Losartan Potssium and Perindopril Erbumine in Combined Tablet Dosage Form

Shaik Mubeena Yasmeen2, P. Sowjanya3, Dr. T. Rajesh4, Dr. Gampa Vijaya Kumar*1 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy. 2,3,4Deapartment of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy. A B S T R A C T A simple, sensitive and precise reverse phase high performance liquid chromatographic method has ... Read More »

Method Development and Validation for Simultaneous Estimation o f Bicalutamide and Atenolol by using RP-HP LC in Bulk and Pharmaceutical Dosage form

Mulla Rafiyuddin*, Akepogu Jayaraju, J. Sreeramulu Department of Chemistry, Sri Krishnadevaraya University, Anantapuramu–515003, Andhra Pradesh, India A B S T R A C T A reverse phase high performance liquid chromatographic method was developed for the determination of Bicalutamide and Atenolol in bulk and pharmaceutical dosage form. The separation was carried out on a [Column: Agilent C18 (4.6 x 250mm, ... Read More »

QSAR Studies of Some Substituted Pyrazole Derivatives against S.aureus

Kishor Arora*1 and Veena Nathani2 1Department of  Chemistry, Govt. P.G. College (Auto.) Datia, M.P.) India 2Department  of  Chemistry, Govt. K.R.G. Auto. P.G. College, Gwalior, M.P, India A B S T R A C T In the present paper QSAR studies related to some novel substituted pyrazole derivatives are reported. All the compounds were evaluated for antimicrobial activity against S.aureus. Their ... Read More »

Development and Validation of RP-HPLC Method for the Estimation of Olmesartan Medoxomil and Chlorethalidone in Tablet Dossage Form

Nidamanuri Vamsi Krishna*, V. Hari Baskar, M. Gobinath, Ramesh Dhani, V. Pavan Kumar, D. Madhu Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the olmesartan medoxomil and chlorethalidone in Tablet dosage form. Chromatogram was run ... Read More »

Chemical Composition and Antimicrobial activity of the Volatile oil of the leaves of Cymbopogon citratus (Lemongrass)

Trivikram Rawat1*, I.P.Pandey2, Suman Lata Chhimwal2 1Member, American Association of Pharmaceutical Scientists, Unites States of America 2Department of Chemistry, D.A.V. (P.G.) College, Dehradun, 248001, India A B S T R A C T The aim of the present study was to investigate the various chemical components present in the volatile oil of leaves of Cymbopogon citratus and to determine its ... Read More »

Green Synthesis of Fulgenic Acids from Stobbe Condensation Method

aYadav Hanuman Singh*, bGadegone Sunita and cPande Hemant bDepartment of Chemistry, Kamla Nehru Mahavidyalaya, Nagpur-440009, India a,cDr. Ira Nimdeokar Research Center for Chemistry, Hislop College, Nagpur 440001, India A B S T R A C T One pot synthesis of acid esters by Stobbe condensation of alkylidene / arylidene succinates and aldehydes or ketones, their subsequent hydrolysis to diacidswerereported. The ... Read More »

Synthesis and Spectral Studies of Novel 3-(5-mercapto-1, 3, 4-oxadiazol-2-yl)-2H-chromen-2-one Derivatives as Anticancer Agents

Chamandeep Kaur Bhinder1*, Amandeep Kaur2 1Department of Pharmaceutical Chemistry, ASBASJSM COP, Bela, Punjab-140111, India 2Department of Pharmaceutical Chemistry, ASBASJSM COP, Bela, Punjab-140111, India A B S T R A C T In recent years, researchers hunt for a novel anticancer agent mainly from plants. Among various phytochemicals, coumarins have attracted considerable interest in the past few years due to their ... Read More »

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