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Category Archives: Chemical Sciences and Chemical research

journal of medicinal chemistry,bioorganic and medicinal chemistry letters,medicinal chemistry research,medicinal chemistry book

UV Spectroscopic Method for Estimation of Enalapril Maleate in Bulk and in its Tablets

UV Spectroscopic Method for Estimation of Enalapril Maleate in Bulk and in its Tablets B. Mohammed Ishaq*, S. Muneer, S. Praveena, B. Famida, Hindustan Abdul Ahad Department of Pharmaceutical Analysis, Balaji College of Pharmacy, Anantapur, AP, India. A B S T R A C T A simple, rapid and sensitive UV spectrophotometric method was developed for the estimation of Enalapril ... Read More »

Various Synthesis Methods of 1,3,4-Oxadiazolederivatives: A Review

M Somashekhar*, R B Kotnal Department of Pharmaceutical Chemistry, Bldea’s College of Pharmacy, Vijaypur-586101. A B S T R A C T Heterocyclic molecules such as Oxadiazoles have been synthesized and evaluated for medical and agricultural activities. The disubstituted Oxadiazoles have executed a range of pharmacologic activities. 1,3,4-oxadiazole and 1,2,4-oxadiazole are better known, and more widely studied by researchers Among ... Read More »

Antinociceptive activity of methanolic extract of Cordia Subcordata Lam. (Boraginaceae) in animal models of nociception

C. Madhavi Latha*1,2, K. Bhaskar Reddy3 1Research Scholar, Pacific University of Higher Education and Research University, Udaipur, Rajastan, India. 2Department of Pharmacology, Jagan’s College of Pharmacy, Nellore, Andhra Pradesh, India. 3Department of Pharmaceutics, Sri Venkateswara College of Pharmacy, RVS Nagar, Chittoor, India. A B S T R A C T Antinociceptive activity of methanolic extract of whole plant of cordial ... Read More »

Method Development and Validation for the Simultaneus Estimation of Olmesartan & Hydrochlorothiazide by using RP-HPLC in Bulk and it’s Pharmaceutical Dosage Form

Valluru Vijayamma*, M. Gobinath, V. Hari Baskar, Ramesh Dhani, V. Pavan Kumar, SK. Kowsar Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidthapolur, Muthkur, Nellore-524346, A.P, India A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Olmesartan Medoxomil   and Hydrochlorothiazide in Tablet dosage form. Chromatogram was run through Inertsil ... Read More »

Analytical Method Development and Validation by RP-HPLC for the Simultaneous Estimation of Linagliptin and Metformin in Bulk and Combined Tablet Dosage Form

G. Varun Kumar*, V. Pavan kumar, M. Gobinath, V. Hari Baskar, Ramesh Dhani, Y. Vijitha Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India A B S T R A C T A new simple accurate and suitable reverse phase high performance liquid chromatographic method was developed for the determination of Metformin and Linagliptin in ... Read More »

Microwave Assisted Synthesis and Antimicrobial activities of 3,4-bis-(4-hydroxy-3-methoxybenzylidene)-7-(N-phenyl)-3,3a,3b,4,5,7-hexahydro-2H-pyrrolo[2,3-c,5,4-c] di pyrazole

Ravindra S. Dhivare1, S. S. Rajput*2 1Department of Chemistry, J.J.T. University, Jhunjhunu, Rajasthan, India 2Department of Chemistry, SVS’s Dadasaheb Rawal College, Dondaicha, Maharashtra, India A B S T R A C T The novel pyrazole derivatives were synthesized by reacting substituted bis-chalcones with 4-hydroxy-3-methoxy benzaldehyde to get 3,4-bis-(4-hydroxy-3-methoxybenzylidene)-7-(N-phenyl)-3,3a,3b,4,5,7-hexahydro -2H-pyrrolo [2,3-c,5,4-c] dipyrazole using solvent-free microwave method. All these derivatives were screened ... Read More »

Development and Validation of RP-HPLC Method for the Estimation of Olmesartan Medoxomil and Cilnidipine in Tablet Dossage Form

Devalam Madhu*, V. Hari Baskar, M. Gobinath, Ramesh Dhani, V. Pavan Kumar, N. Vamsi Krishna Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Olmesartan medoxomil and Cilnidipine in Tablet dosage form. Chromatogram was run ... Read More »

Synthesis, Characterization and Biological Activity Evaluation of Some 2-(1, 1-Dimethyl Guanidinyl)-4,5-Diaryl Imidazoles

B. Geetha* Pharmacist, Plot No.1, H.No.8-3, SVU Non-Teaching Colony, Opposite Vidyanagar colony, Tirupati-517502 A B S T R A C T A series of 2-(1,1-dimethyl guanidinyl)-4,5-diaryl imidazoles are synthesized by condensing 2-hydroxy -1,2-diaryl ethanones with metformin. All the compounds were characterized and screened for their anthelminthic and anti-tubercular activity. Most of the compounds exhibit both the activities. Keywords: Aromatic aldehydes, ... Read More »

Analytical Method Development and Validation by RP-HPLC for Simultaneous Estimation of Isoniazid and Ethambutol in Combined Tablet Dosage Form

Gampa Vijaya Kumar1*, N. Rajendra Prasad2 1Professor, Departmernt of Pharmaceutical Analysis, CVM College of Pharmacy, Velichala, Kothapally, Karimnagar, Telangana-505451 2Asst. Professor, Departmernt of Pharmaceutical Analysis, CVM College of Pharmacy, Velichala, Kothapally, Karimnagar, Telangana-505451 A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Isoniazid and Ethambutol in Tablet dosage ... Read More »

Analytical Method Development and Validation by RP-HPLC for Simultaneous Estimation of Lopinavir and Ritonavir in Combined Tablet Dosage form

Gampa Vijaya Kumar1*, N. Rajendra Prasad2                                                                                                             ... Read More »

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