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Category Archives: Chemical Sciences and Chemical research

journal of medicinal chemistry,bioorganic and medicinal chemistry letters,medicinal chemistry research,medicinal chemistry book

Analytical Method Development and Validation by RP-HPLC for Simultaneous Estimation of Ketorolac and Febuxostat in Combined Tablet Dosage Form

Gampa Vijaya Kumar*1, Dr. P. Shashikala2 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Keesara, Rangareddy, Telangana, India 2Professor, Department of Pharmaceuticals and fine Chemicals, University College of Technology, Osmania University, Hyderabad, Telangana, India.  A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the ... Read More »

Zinc Oxide Nanoparticles for Choosy Disastrous of Tumor Cells and Potential for Medicine Freighting Uses

Kiran Mishra* Applied Sciences Department, Chandigarh Engineering College, Landran, Mohali, Punjab, India A B S T R A C T Nanotechnology speaks to another and empowering stage that guarantees to give an expansive scope of novel uses and enhanced advances for organic and biomedical applications. This ultra-little size is practically identical to actually happening proteins and biomolecules in the phone ... Read More »

Discerning Sarcosine Biosensor in the Presence of Elevated Concentrations of Ascorbic Acid and Uric Acid

S. Brillians Revin* Assistant Professor, Department of Chemistry (MSc., Ph.D, Post-doctoral Research Scientist-South Korea, 2012-2014), Francis Xavier Engineering College, Scad Group of Institutions,Tirunelveli, India. A B S T R A C T The electrochemical response of Sarcosine (Sar) in the presence of elevated concentrations of Ascorbic acid (AA) and Uric acid (UA) is reported by differential pulse voltammetry (DPV) using ... Read More »

Analytical Method Development and Validation for Sumultaneous Estimation of Asparin and Atrovastatin Calcium in Combind Dosage form by using UV- Spectrophotometry

V. Aparna*, D. Sireesha, Dr. Vasudha bakshi Department of Pharmaceutical Analysis and Quality assurance, Anurag group of institutions (Formerly Lalitha college of pharmacy), Hyderabad, Telangana, India A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Aspirin   and Atorvastatin calcium in Tablet dosage form. Solutions of Aspirin and Atorvostatin ... Read More »

Validated RP-HPLC Method Development for the Simultaneous Estimation of Lisinopril and Hydrochlorthiazide in Bulk and Pharmaceutical Dosage Form

Amarnath Mundra*, Harshini.S, Sireesha. D, Akifulhaque, Vasudha.B Department of Pharmaceutical Analysis and Quality assurance, Anurag group of institutions (Formerly Lalitha college of pharmacy), Hyderabad. A B S T R A C T A simple and cost effective RP-HPLC method is described for the determination of lisinopril and Hydrochlorothiazide in pure form and in pharmaceutical formulations. The drug was highly soluble ... Read More »

Isolation, Characterization, and Biological Activities of Gossweilerine, an Unusual Quaternary Alkaloid from Drypetes Gossweileri

Joseph Ngoupayo1, Turibio K. Tabopda2*, Muhammad Shaiq Ali3, Marie-Aleth Lacaille-Dubois4 1Faculty of Medicine and Biomedical Sciences; BP 1364 Yaoundé, Cameroun 2Département de Chimie Organique, Université de Yaoundé I ; BP 812 Yaoundé, Cameroon, 3H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan and 4Laboratoire de Pharmacognosie, UMIB UPRES EA 3660, Faculté de Pharmacie, ... Read More »

Separation of Kawain, Flavokawain and 1,7-Diphenyl-5-hydroxy-6-heptene-3-one from the Rhizomes of Alipinia mutica using SWE-CNCC purification column technique

Yousif Jumaa A. Alrahmana, Mohd Marsin Sanagia,b, Abdulrahman Alzandic Hasnah Mohd Siratd , Wan Aini Wan Ibrahimd and Hassan Y. Aboul-Eneinde aDepartment of Chemistry, Faculty of Science and arts, Albaha University The kingdom of Saudi arabia bIbnu Sina Institute for Fundamental Science Studies, Nanotechnology Research Alliance, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Johor, Malaysiya. cDean of faculty of science and ... Read More »

Emulsification of Neem oil: effect of polar solvents and chain length of surfactant

Manisha Bhattacharya*, S.G. Dixit RJ College, Ghatkopar, Mumbai, UICT, Matunga, Mumbai, India A B S T R A C T Neem oil was emulsified by using surfactant mixture oleic acid and Tween 20,40, 60, 80, etc. The dispersion medium used for these emulsions were distilled water, water-ethylene glycol, water-formaide, water-glycerol. Compositions of these binary mixtures were varied by changing the ... Read More »

Metal Complexes of (E)-N-(2-ethoxyphenyl)-2-(mercapto-phenylamino-methylene)-3-oxo-butanamide (EPMPB): Preparation, Characterization and Biological Activity

Ahmed. A. Gahlan* Chemistry Department, Faculty of Science, Al-Azhar University, Assiut branch, 71524, Assiut, Egypt A B S T R A C T Some novel transition metal [V(V), Co(II), Ni(II), Cu(II) and Cd(II)] complexes of (EPMPB) have been synthesized and characterized. Complexes were isolated in solid state and characterized by elemental analyses, electronic spectra, thermal method (TGA and DTA), IR and ... Read More »

Green Synthesis of Itaconic Acids from Stobbe Condensation Method

Yadav Hanuman Singh1, Gadegone Sunita2 and Pande Hemant3 1, 3Dr. Ira Nimdeokar Research Center for Chemistry, Hislop College, Nagpur 440001, India 2Department of Chemistry, Kamla Nehru Mahavidyalaya, Nagpur 440009, India A B S T R A C T One pot synthesis of acid esters by Stobbe condensation of alkylidene / arylidene succinates and aldehydes or ketones, their subsequent hydrolysis to ... Read More »

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