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Category Archives: Chemical Sciences and Chemical research

journal of medicinal chemistry,bioorganic and medicinal chemistry letters,medicinal chemistry research,medicinal chemistry book

Exploiting the Antiparasitic Activity of Naphthalimides Derivatives

Gabriela Cristo1,2, Luís Gaspar1,2, Jennifer Noro3, Catarina Baptista1,2, Paul Kong Thoo-Lin4, Maria José Alves3 and Anabela Cordeiro-da-Silva1,2,5,* 1Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal 2IBMC-Institute for Molecular and Cell Biology, Parasite Disease Group, Porto, Portugal 3Department of Chemistry, Campus de Gualtar, University of Minho, Braga, Portugal 4School of Pharmacy and Life Sciences, Robert Gordon University, ... Read More »

The Anti-corrosive Characteristics of Betalains on Cu metal

Jinendra Singh Chauhan1 and D. K. Gupta2 1Sagar Institute of research and Technology Bhopal (M.P.), India-462041. 2Institute of Excellence in Higher Education, Bhopal (M.P.), India-462041. A B S T R A C T The use of Betalains Cu corrosion behavior was tested in aerated aqueous solutions of KCl for different pH values. Polarization resistance (Rp) measurements, Polarization curves and AC ... Read More »

Antidiabetic Activity of a Polyherbal Preparation in Streptozotocin-Nicotinamide (STZ-NICO) Induced Diabetic Rats

Amit Agrawal1, Ameeta Argal2 1Research Scholar, Institute of Pharmaceutical Science & Research Center, Bhagwant University, Ajmer, Rajasthan, India-305004 2Professor, TIT College of Pharmacy, Bhopal, Madhya Pradesh, India-462042 A B S T R A C T The present work was executed to evaluate the anti-diabetic potency of a polyherbal preparation. The objective of this study is to induce experimental diabetes mellitus ... Read More »

One Pot Synthesis of Fulgenic Acids from Stobbe Condensation Method

Yadav Hanuman Singh1,Gadegone Sunita2 and Pande Hemant1 1Dr. Ira Nimdeokar Research Center for Chemistry, Hislop College, Nagpur 440001, India. 2Department of Chemistry, Kamla Nehru Mahavidyalaya, Nagpur 440009, India. A B S T R A C T One pot synthesis of acid esters by Stobbe condensation of alkylidene / arylidene succinates and aldehydes or ketones, their subsequent hydrolysis to diacids were ... Read More »

Design and Characterization of Chronotherapeutic Drug Delivery System of Dexibuprofen for the Treatment of Arthritis

Kishor*1, Bindu Madhavi2, K. Someshwar2 1Department of Pharmceutics, St. Pauls College of Pharmacy, Hyderabad, Telangana, India 2Manager, Formulation R&D, KP Labs (A Division of KDPL), Kothapet, Hyderabad Telangana, India A B S T R A C T In the present research work, chronotherapeutic drug delivery of Dexibuprofen was carried out. Chronotherapeutics refers to a treatment method in which in-vivo drug ... Read More »

Formulation Development and In -Vitro Evaluation of Bilayer Tablets Containing Dimenhydrinate and Cinnarizine

Kiran Kumar Yada1*, Dharmajit Pattanayak1, Saumya Das1, Vagdevi Y2 1Associate Professor, Vikas college of pharmaceutical sciences, Rayanigudem, Suryapet. 2Research Assistant, KP Labs, Kothapet (A Division of KDPL), Hyderabad. A B S T R A C T The conclusions  arrived  in  this  thesis  indicated  that  the  formulations  of Dimenhydrinate sustained in  this  investigation  was  found  to  be  satisfactory  based  on  in-vitro  release  ... Read More »

A Review on Thyroid Disease

B. Kumar*, K. Durga Prasanna Roja,  M. Gobinath Department of Pharmacy Practice, Ratnam Institute of Pharmacy, Pidthapolur, Nellore. A B S T R A C T The thyroid gland is one of the largest endocrine gland and consists of two connected lobes. The thyroid gland is found in the neck, below the thyroid cartilage. It participates in these processes by producing thyroid hormones, the principal ones ... Read More »

Development and Validation of New UV Spectroscopic and HPLC Methods for the Estimation of Zidovudine in Bulk and Pharmaceutical Dosage Form

Telugu Naga Mohan, Shaik Mohammed Yusuf*, Seerla Eswaraiah, D. Chinna Raju, E. Vijay Kumar Srinivasa Institute of Pharmaceutical sciences, Proddatur, YSR Kadapa [Dist]. AP. India.  A B S T R A C T In the present work, two simple, sensitive and specific methods (UV Spectroscopy and RP-HPLC) have been developed for the quantitative estimation of Zidovudine in bulk and pharmaceutical ... Read More »

Simultaneous Estimation Amitriptyline Hydrochloride and Chlordiazepoxide by HPLC Method

Seerla Eswaraiah, Shaik Mohammed Yusuf*, T. Naga Mohan, D. Chinna Raju, E. Vijay Kumar Srinivasa Institute of Pharmaceutical Sciences, Proddatur, YSR Kadapa, A.P. India A B S T R A C T A simple, economic, selective, precise, and accurate Reverse Phase High Performance Liquid Chromatography method for analysis of Amitriptyline HCl & Chlordiazepoxide in tablet dosage form was developed and ... Read More »

Method Development and Validation by RP-HPLC for the Simultaneous Estimation of Cinacalcet and Maxacalcitol in Tablet Dosage Form

N. Usha*, M. Gobinath, V. Hari Baskar, Ramesh Dhani, A. Soniya Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India.  A B S T R A C T A Simple, selective, accurate, precise and linear RP-HPLC method was developed subsequently validated for estimation of cinacalcet in bulk & tablet dosage form. Gradient elution at a ... Read More »

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