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Category Archives: Chemical Sciences and Chemical research

journal of medicinal chemistry,bioorganic and medicinal chemistry letters,medicinal chemistry research,medicinal chemistry book

Design and In-Vitro Characterization of ORO Dispersible Tablets of Azithromycin

H. Padmalatha*  HOD, Pharmaceutical analysis and QA, Gyana Jyothi College of Pharmacy, Boduppal, Hyderabad. A B S T R A C T The goal of this project is to formulate Oro-dispersible tablet of Azithromycin that is intended to disintegrate rapidly into the oral cavity and form a stabilized dispersion. A direct compression method was failed to formulate dispersible tablet of ... Read More »

Evaluation of Anticonvulsant Activity of Leaf Extracts of Ailanthus Glandulosa (Linn) Planch in Experimental Animals

P. Naresh Babu1, M. Gobinath2, M. Lakshmidevi*1, SK. Karimulla1, Ramesh Dhani2  1Department of Pharmacology, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India. 2Department of Pharmaceutical Chemistry, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore, A.P, India. A B S T R A C T Ailanthus glandulosa (Linn). Planch has been used from long time in traditional medicine. The main ... Read More »

Pulsincap Osmotically Driven Capsule Based On Push-Pull Technology: An Overview

Shaikh Siraj N*, G.J. Khan, Shaikh Mohsin F, Fakir Hina S, Shaoor Ahmad S, Shaikh Salman I. Department of Pharmaceutics, Ali Allana college of Pharmacy, Akkalkuwa, Dist. Nandurbar (M.S.), India. A B S T R A C T Pulsatile systems are offers a more of attraction because as they deliver the drug at the right amount, right site of action ... Read More »

Anti-oxidant and Anti-inflammatory activity of Tabebuiarosea (Flowers)

S. Solomon1*, N. Muruganantham2, M. M. Senthamilselvi3 1Department of Chemistry, Periyar E.V.R.College (Autonomous), Trichy, Tamil Nadu, India. 2Department of Chemistry, Roever Engineering College, Perambalur, Tamil Nadu, India 3Principal, Government Arts College, Ariyalur, Tamil Nadu, India. A B S T R A C T The aim of this study is to investigate the anti-inflammatory and anti-oxidant activities of the sample isolated ... Read More »

The Assessment of Fluoride levels in Ground Water of Mydukur Municipality of YSR Kadapa Dt., A.P, India

A. Ramesh Babu*1, S. Pavan Kalyan1, P. Suresh1, B. Rajeswari1, M. V. Hari Prasad1, B. Muralidhara Reddy2 and V. Sunitha2 1Dept.of Chemistry, SCNR Govt. Degree College, Proddatur, YSR Kadapa dist, A.P, India 2Dept.of Geology and Geo informatics, Yogi Vemana University, Kadap, A.P, India A B S T R A C T Potentiometric analysis is used for the determination fluoride levels ... Read More »

Pharmacodynamic and Pharmacokinetic Drug Interaction of Risperidone with Pioglitazone

Bhupalam Pradeep kumar*1, Y. Padmanabha Reddy2, N. Devanna3 1Department of Pharmacology, Center for Pharmaceutical Research, Raghavendra Institute of Pharmaceutical Education and Research, Anantapuramu-515721, Andhra Pardesh, India. 2Principal, Raghavendra Institute of Pharmaceutical Education and Research, Anantapuramu-515721, A.P, India. 3Principal, JNTUA College of Engineering, Kalikiri-515234, Andhra Pardesh, India. A B S T R A C T The present study was performed to ... Read More »

Synthesis, Characterization, Biological Evaluation and Docking studies of 2-(benzyl sulfonyl)-5-(3-(4-(trifluoromethyl)phenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)-1,3,4-oxadiazole Derivatives

G. Govindu*, D. Rajesh, P. Raveendra Reddy, L.K. Ravindranath Department of chemistry, Sri Krishnadevaraya University, Anantapuramu, A.P-India A B S T R A C T New novel derivatives of 2-((4- substituted benzyl)sulfonyl)-5-(3-(4-( substituted phenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)-1,3,4-oxadiazoles  (9a-l as per scheme-I)were prepared by condensation of 2-(4-hydrazinylpyrimidin-5-yl)-5-((4-substituted benzyl)sulfonyl)-1,3,4-oxadiazole (8a-f) with various 4-substituted benzoic acids. The synthon 8a-f were obtained by the refluxing of 2-(4-chloropyrimidin-5-yl)-5-((4-substituted ... Read More »

Synthesis of Cyclohexane Carboxylic acid 1-(phenyl amino)-methyl ester: intermediate important in the production of carfentanil

Amir Hossein Zamani*, Hamid Reza Ghaienia Malek Ashtar University of Technology, Tehran, Iran, 1465943681 A B S T R A C T In this process synthesis of Cyclohexane Carboxylic acid, 1-(phenyl amino) – methyl ester is described. These intermediate important can be utilized in the production of commercial synthetic analgesics carfentanil. In summary, we have developed an efficient and original ... Read More »

Exploiting the Antiparasitic Activity of Naphthalimides Derivatives

Gabriela Cristo1,2, Luís Gaspar1,2, Jennifer Noro3, Catarina Baptista1,2, Paul Kong Thoo-Lin4, Maria José Alves3 and Anabela Cordeiro-da-Silva1,2,5,* 1Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal 2IBMC-Institute for Molecular and Cell Biology, Parasite Disease Group, Porto, Portugal 3Department of Chemistry, Campus de Gualtar, University of Minho, Braga, Portugal 4School of Pharmacy and Life Sciences, Robert Gordon University, ... Read More »

The Anti-corrosive Characteristics of Betalains on Cu metal

Jinendra Singh Chauhan1 and D. K. Gupta2 1Sagar Institute of research and Technology Bhopal (M.P.), India-462041. 2Institute of Excellence in Higher Education, Bhopal (M.P.), India-462041. A B S T R A C T The use of Betalains Cu corrosion behavior was tested in aerated aqueous solutions of KCl for different pH values. Polarization resistance (Rp) measurements, Polarization curves and AC ... Read More »

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