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Siddharth A. Waghmare1*, Dipak T. Tayade2 1Department of Chemistry, Ghulam Nabi Azad College, Arshitakli, Dist. Akola-444 404 (MS) India. 2Department if Chemistry, Govt. Vidarbha Institute of Science & Humanities, Amravati-444 604(MS) India A B S T R A C T Present research work involves, Synthesis of novel series of (2E)-1-[4-(2,4-dithio-3-phenyl-5-substituted-1,3,5-triazino-6-yl)aminophenyl]-3-(3,4-dimethoxyphenyl)prop-2-en-1-one (IIa-e) by the isomerisation of series of (2E)-1-[4-(2-phenylimino-4-substitutedimino)amino-1,3,5-dithiazino-6-yl)aminophenyl]-3-(3,4-dimethoxyphenyl)prop-2-en-1-one (Ia-e) under ... Read More »
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Category Archives: Chemical Sciences and Chemical research
Effect of surfactants on the Acid catalyzed hydrolysis of aliphatic esters having variation in chain length of their alkyl part
Asok K. Jana*1, D. Vijayasarathi1 and Papiya Jana2 1Department of Chemistry, Kanchi Mamunivar Centre for Post Graduate Studies, Pondicherry – 605 008, India. 2Departments of Chemistry, Sri Manakula Vinayagar Engineering College, Pondicherry -605107, India A B S T R A C T The kinetics of acidic hydrolysis of simple aliphatic esters in aqueous and surfactant media has been studied. Different ... Read More »
Green Synthesis of Zinc Nanoparticles using Punica granatum Fruit Extract and their Structural and Optical Properties
R. Rajakumari*1, 1S. Kalaiarasi, 2L.Parimala 1PG and Research Department of Physics, Queen Mary’s College (Autonomous), Chennai, Tamil Nadu, India 2Annai Violet College of Arts & Science, Chennai, Tamil Nadu, India A B S T R A C T The Zinc nanoparticles were prepared with the fruit extract of Punica granatum via green synthesis. Though physical and chemical methods are more ... Read More »
Analytical Method Development and Validation for the Simultaneous Estimation of Darunavir and Cobicistat by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form
Sd. Asra Ayesha*, G. Devika Subramaniyan Bomma Institute of Pharmacy, Allipuram, Khammam, Telangana, India A B S T R A C T A new, simple, precise, accurate and reproducible RP-HPLC method for simultaneous estimation of Darunavir and Cobicistat in bulk and pharmaceutical formulations was developed. Separation of Darunavir and Cobicistat was successfully achieved on C18 ODS(250mm x 4.6 mm), 5µm., ... Read More »
Analytical Method Development and Validation for the Estimation of Erlotinib Hydrochloride by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form
Gobala Krishnan P*, Munisekhar V, Ranjit Singh B. Rathore Department of Pharmaceutical Chemistry, Vagdevi college of Pharmacy & Research centre, Nellore, Andhra Pradesh, India. A B S T R A C T The chromatographic conditions were successfully developed for the separation of Erlotinib hydrochloride by using the HPLC method for Erlotinib hydrochloride as per ICH Guide lines. Shimadzu LC-2010 series ... Read More »
Simultaneous Estimation Method for the Determination of Rosuvastatin and Ezetimibe from their Combination Tablet Dosage form Using RP-HPLC
S. Mehboob Basha, Shaik Mohmmed Yusuf*, Vummadi Sai Chandana, Bumireddy Pavani, E. Vijay Kumar Department of Pharmaceutical Analysis, Srinivasa Institute of Pharmaceutical Sciences, Proddatur, YSR Kadapa, A.P. India A B S T R A C T Rosuvastatin is an HMG Co-A inhibitor and Ezetimibe is an intestinal cholesterol absorption inhibitor. The combination formulation is used for the treatment of hypercholestrolemia. A ... Read More »
Validated RP-HPLC Method for Simultaneous Estimation of Metformin and Vildagliptin in Its Tablets
Karem Kishore Kumar Reddy, Shaik Mohammed Yusuf*, E. Vijay Kumar, Bumireddy Pavani, E. Divya, Vummadi Sai Chandana Department of Pharmaceutical Analysis, Srinivasa Institute of Pharmaceutical Sciences, Proddatur, YSR Kadapa, A.P. India A B S T R A C T A simple, rapid, sensitive and robust reversed phase-HPLC method was developed and validated to measure simultaneously the amount of Metformin and Vildagliptin ... Read More »
A Review on Newer Trends in Treatment for Diabetes Management in Health Care Practice
A. Bharath kumar1*, S.P. Zakiullah1, B. Kumar1, Sk. Kareemulla1, Ramesh Dhani2 1Department of Pharmacy Practice, Annamcharya college of Pharmacy, Rajampet, A.P, India-518218 2Department of Pharmaceutical Chemistry, Ratnam Institute of Pharmacy, Nellore, A.P, India-524346. A B S T R A C T It is a group of metabolic diseases in which there is high blood sugar levels over a prolonged period. ... Read More »
Anti-Diabetic Effect of Diospyros Malabarica against Alloxan Induced Diabetes in Rats
A. Ravi Kumar1*, P. Vengalrao1, S. Satyanarayana1, Gireesh Jampana1, Matle Naga Priyanka2 1Celon Laboratories Private Limited, Aleap Industrial Estate, Gajularamaram, R.R. Dist., Telgana-500090 2Department of Pharmaceutical Analysis Narayana Pharmacy College, Nellore, Andhra Pradesh, India A B S T R A C T The Present study was under taken to evaluation of anti-diabetic potential of Diospyros malabarica(DM) leaves in low dose ... Read More »
Development and Validation of RP-HPLC Method for the Estimation of Sitagliptin Phosphate in Bulk and Its Tablet Dosage Form
I. Arulraj1, P. Vembu2 and A. Chenthilnathan1* 1Department of Pharmaceutical Chemistry, Manonmaniam Sundaranar University, Tirunelveli – 627 012, Tamil Nadu, India. 2Bafna Pharmaceuticals Limited, Grantlyon village, Chennai – 600 052, Tamil Nadu, India. A B S T R A C T A simple and sensitive reversed-phase liquid chromatographic method has been developed and validated for the estimation of Sitagliptin phosphate ... Read More »
