B. Wankhede* and A. B. Patil Department of Chemistry, P. N.College, Pusad, 445216 (M. S.) India A B S T R A C T Now a day’s the remarkable biological activity of hydrazone and the dependence of their mode of chelation with metal ions present in living system have been a significant interest. Inspite of a large number of antibiotics ... Read More »
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Category Archives: Chemical Sciences and Chemical research
Amperometric sensor of Cytosine by heterocyclic polymer fabricated glassy carbon electrode
Brillians Revin1*, M. Amal Raj2 1Assistant Professor, Department of Chemistry, Francis Xavier Engineering College, (Post-doctoral Research Scientist, Pusan National University (2012-2014) South Korea), Scad Group of Institutions, Tirunelveli – 627003, Tamilnadu, India. 2Assistant Professor, Department of Chemistry, Loyola College, (Post-doctoral Research Scientist (2014-2015) South Korea) Nungambakkam – 600034, Tamilnadu, India A B S T R A C T The electrochemical ... Read More »
Analytical Method Development and Validation for the Simultaneous Estimation of Enalapril and Hydrochlorothiazide by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form
Jyothi Keerthi*, G. Devika Subramaniyan, Ramesh Petchi, Rajendran Bomma Institute of Pharmacy, Allipuram, Khammam, Telangana, India A B S T R A C T A Reverse Phase High Performance Liquid Chromatography method was developed for the determination of Enalapril and Hydrochlorothiazide in bulk and Pharmaceutical dosage form. The separation was achieved on an Inertsil ODS (250×4.6mm),5µm column by using a ... Read More »
Analytical Method Development and Validation for the Simultaneous Estimation of Raltegravir and Lamivudine by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form
Parsa Sivarama Krishna*, G. Devika Subramaniyan, Ramesh Petchi, Rajendran Bomma Institute of Pharmacy, Allipuram, Khammam, Telangana A B S T R A C T A simple, accurate, precise method was developed for the simultaneous estimation of the Raltegravir and Lamivudine in Tablet dosage form. Chromatogram was run through Inertsil ODS 3V(250×4.6mm)5µm column by using a mixture of Phosphate buffer and ... Read More »
N-[4-[Benzyloxy] benzyl]-benzenemethaneamines with High Biological Activity against Intracellular Trypanosoma cruzi and Leishmania infantum Amastigotes
Gabrielle Frizzo Souza1, Simon Bernhard Cämmerer1*, Caio Haddad Franco2, Laura Maria Alcantara2, Carolina Borsoi Moraes2, Lucio Holanda Freitas Junior2* 1Instituto de Química, Universidade Estadual de Campinas, Rua Monteiro Lobato S/N, Cidade Universitaria Zeferino Vaz, Barão Geraldo, CP 6154, CEP 13083-970, Campinas, São Paulo, Brasil. 2Laboratório Nacional de Biociências (LNBio), Centro Nacional de Pesquisa em Energia e Materiais (CNPEM), Rua Giuseppe ... Read More »
Development and Validation of Stability Indicating RP-HPLC Method for Amoxicillin and Clavulanate Potassium Related Impurities in Pharmaceutical Dosage Forms
Konda Sidda Reddy*1, Ramamohana Reddy Maddike2, J Sreeramulu2 1Department of Chemistry, Rayalaseema University, Kurnool, Andhra Pradesh, India. 2Departments of Chemistry, Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India A B S T R A C T A simple, cost effective, stability indicating reversed-phase High Performance Liquid Chromatography method was developed for separation and quantification of seventeen specified known related impurities in ... Read More »
A Green Alternative Approach for Synthesis of 2-Substituted Benzothiazoles Catalysed by NBS in Ultra Sonication Method
Dr. P. Thriveni*, K.P.V. Subba Rao, M. Hari Krishna Department of Chemistry, Vikrama Simhapuri University, Nellore-524003, A.P, India. A B S T R A C T NBS is an efficient, readily available and cheap catalyst for the synthesis of 2-substituted benzothiazole derivatives by condensation of 2-aminothiophenol and aldehydes under sonication conditions by application of green solvents. This protocol is very ... Read More »
Analytical Method Development and Validation for the Simultaneous Estimation of Atenolol and Nitrendipine by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form
Gobala Krishnan P*, Munisekhar V, Ranjit Singh B. Rathore Department of Pharmaceutical Chemistry, Vagdevi College of Pharmacy & Research Centre, Nellore, A.P, India A B S T R A C T A new method was established for simultaneous estimation of Atenolol and Nitrendipine by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Atenolol and Nitrendipine by ... Read More »
Extraction and Application of Lycopene from Papaya
Ms. Harini R & Dr. V. Judia Harriet Sumathy* Postgraduate & Research Department of Biotechnology, Women’s Christian College, Chennai–600 006. A B S T R A C T Lycopene a carotenoid in the same family as beta-carotene, is what gives tomatoes, pink grapefruit, apricots, red oranges, watermelon, and guava their red color. Lycopene is not merely a pigment, it is ... Read More »
Analytical Method Development and Validation for the Simultaneous Estimation of Fluticasone and Vilanterol by RP-HPLC Method in its Pharmaceutical Dosage Forms
Swapna1, P. Sowjanya1, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T A new method was established for simultaneous estimation of fluticasone and vilanterol by RP-HPLC method. The chromatographicconditionsweresuccessfullydevelopedfortheseparationoffluticasone ... Read More »