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Category Archives: Chemical Sciences and Chemical research

journal of medicinal chemistry,bioorganic and medicinal chemistry letters,medicinal chemistry research,medicinal chemistry book

A Review on Quinazolines as Anticancer Agents

A. Gopi Reddy*1, V. Harinadha Babu1*, Y. Jaya Prakash Rao2 1Department of Pharmaceutical Chemistry, G. Pulla Reddy College of Pharmacy, Hyderabad, India. 2Department of Chemistry, Telangana University, Nizamabad, India A B S T R A C T The present study was carried out on Zolmitriptan Mouth dissolving tablets were prepared by direct compression method and different concentration super disintegrants like ... Read More »

Evaluation of anthelmintic and In-vitro antioxidant Activities of plectranthus amboinicus

Garla Venkateswarlu*1, Dr. P. Venkatesh2, Dr. Hepcy kalarani3, E. Rajani4, M.P Vijay Kumar5 1Assistant professor, Dept. of pharmaceutical chemistry, Jagan’s College of Pharmacy, Nellore, A.P, India. 2Principal, Depatrment of pharmaceutical chemistry, Jagan’s College of Pharmacy, Nellore, A.P, India. 3HOD & Professor, Dept. of pharmaceutical chemistry, Jagan’s College of Pharmacy, Nellore, A.P, India. 4Assistant professor, Depatrment of pharmacology, Jagan’s College of ... Read More »

Method Development and Validation of Voglibose in pure and Pharmaceutical Dosage form by RP-HPLC

Jogu Anitha*, P. Sunitha, Vijaya Kuchana Department of Pharmaceutical Analysis, Teegala Krishna Reddy College of Pharmacy, Meerpet, Hyderbad. A B S T R A C T The chromatographic conditions were successfully developed for the separation of Voglibose by Deveosil ODS-HG-5 C18 (250×4.6mm, 5cm) column. Flow rate was 1ml/min, mobile phase ratio was 70:30% v/v Acetonitrile : Buffer, UV detection at ... Read More »

Synthesis and In-silico Studies of Novel Methylene Bridge Derivatives of Anthracene

G.T. Roopesh*, N. Sreelekha, P. Susmitha, P. Pallavi, M. Maniteja, B. Swapna Balaji college of pharmacy, Dept. of Pharmaceutical Chemistry Ananthapuramu, A.P, India. A B S T R A C T The present work was aimed to Synthesise and carryout Insilico studies of Methylene Bridge Derivatives of anthracene. Anthracene is mainly converted to anthraquinone, a precursor to dyes. The anthracene ... Read More »

Design and Characterization of Mouth Dissolving Tablets of Zolmitriptan Using Novel Super Disintegrants

Hareesh Dara*, Ampati Srinivas St John College of Pharmacy, Hasanparthy, Hanamkonda, Telangana, India A B S T R A C T The present study was carried out on Zolmitriptan Mouth dissolving tablets were prepared by direct compression method and different concentration super disintegrants like croscarmellose sodium, polyplasdone XL and Explotab were used in mouth dissolving tablets. A total of 9 ... Read More »

Synthesis and Characterization of New Di Phenyl Quinoxaline Derivatives

C. Ramakrishna*, G. Saikrupa, S. Hanumantha rayappa, V. Visnu kumar, B. Swapna, S.Brahmani Bai, Dr. M. Geetha vani Balaji College of Pharmacy, Department of Pharmaceutical Chemistry Ananthapuramu, A.P, India. A B S T R A C T The heterocyclic compounds are very much used as anti microbial agents. Quinoxalines are an important class of nitrogen containing heterocyclic with wide variety ... Read More »

Synthesis Characterization and Anthelmintic Activity of Acid Hydrazides

C. Ramakrishna*, B. Sandhya, G. Saijyothi, D. Komala, G. Anveshkumar, Dr. M. Geetha Vani Balaji College of Pharmacy, Department of Pharmaceutical Chemistry, Ananthapuramu, A.P, India. A B S T R A C T Synthesis & evaluation acid Hydrazides and their derivatives for their anthelmintic activity was determined. Synthesized the acid Hydrazides derivatives (BPO-1 to BPC-4). When Hydrazides are conjugates with ... Read More »

Method Development and Validation of Metformin in Pure and Its Tablet Dosage Form by using RP-HPLC

Dr. Hareesh Dara, Meesa Rajendar, Dr. D Siva Dinesh St John College of Pharmcy, Hasanparthy, Hanamkonda, Telangana, India A B S T R A C T High Performance Liquid Chromatography is now one of the most powerful tools in analytical chemistry. It has the ability to separate, identify, and quantitative the compounds that are present in any sample that can ... Read More »

RP-HPLC Method Development and Validation for Simultaneous Estimation of Ledipasvir and Sofosbuvir in Bulk and Tablets

P. Vamsi Reddy*1, V. Asha Ranjani2, R. Chandra Sekhar3, M. Shyam Sundar3 1Centre for Pharmaceutical Sciences, IST, JNTU, Hyderabad -500085 2MLR Institute of Pharmacy, Dundigal (v), Hyderabad-500043 3Department of Pharmaceutical analysis& Quality assurance, OU, Hyderabad-500007 A B S T R A C T The present paper describes a new, simple, precise, and accurate RP-HPLC method for simultaneous estimation of ledipasvir ... Read More »

Method Development and Validation of Olodaterol and Tiotropium by RP-HPLC Method

Farhana Shaheen*, Salma Begum, Rubina Kauser, Airaj Mahajabeen, MD Muzammil Hassan MRM College of Pharmacy, Chintapalliguda, Ibrahimpatnam, R.R District-501510 A B S T R A C T Reverse phase high-performance liquid chromatography (RP-HPLC) involves the separation of molecules on the basis of hydrophobicity. The separation depends on the hydrophobic binding of the solute molecule from the mobile phase to the ... Read More »

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