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Dr. K. Nageswara Rao1*, Raghava Doonaboyina2, Bhavani3 1Professor and Head, Department of Pharmaceutical Analysis, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 2Associate Professor and Head, Department of Pharmaceutical Chemistry, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 3K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. A B ... Read More »
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Category Archives: Chemical Sciences and Chemical research
Stability Indicating RP-HPLC Method for Simultaneous Estimation of Lumacaftor and Ivacaftor in Bulk and Pharmaceutical Dosage Forms
Rameeja Pattan*, V. Haribaskar, Pasala Sandhya Mounika, Ramesh Dhani, B. Prathap Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore A B S T R A C T A simple, fast, accurate, precise, reproducible Stability indicating Reverse phase High performance liquid chromatography (RP-HPLC) method was developed and validated for the determination of Lumacaftor and Ivacaftor in Bulk and ... Read More »
Method Development and Validation of Acetazolamide Single Drug Molecule by Using UV Double Beam Spectrophotometer
Rameeja Pattan*, M. Charitha, M. Hemalatha, C. Lalitha, P. Pravallika, M. Vyshnavi, V. Sneha Priya Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore-524 346, Andhra Pradesh A B S T R A C T This UV-spectrophotometric technique is quite simple, accurate, precise, reproducible, and sensitive. The UV method has been developed for quantification of Acetazolamide in tablet formulation. The validation ... Read More »
Male Antifertility Activity of Hydro-Alcoholic Stem and Leaf Extracts of Ecballium Elaterium on Male Wistar Rats
1Sarath Chandiran Irisappan, 2Jaya Kumar Annamalai* 1Professor, Sun Institute of Pharmaceutical Education and Research, Nellore, A.P, India-524346 2Research Scholar, PRIST University, Thanjavur, Tamilnadu, India- 613403 A B S T R A C T Objective: The objective was to investigate the male antifertility effect of hydro-alcoholic stem and leaf extracts of Ecballium elaterium on male Wistar rats. Methods: The animals were divided ... Read More »
Green Chemistry for Environmental Sustainability: The waste reduction approach
Deepak M. Nagrik*, Damodar M. Ambhore£ *Department of Chemistry, G.S.College, Khamgaon, Distt. Buldana, M.S., India-444303 £Department of Chemistry, Shri Pundlik Maharaj Mahavidyalaya, Nandura, Dist. Buldana, M.S., India-443404 A B S T R A C T “Green Chemistry” is the universally accepted term to describe the movement towards more environmentally acceptable chemical processes and products. It encompasses education, research, and commercial ... Read More »
Synthesis of N-(3-Oxo-2,4-dihydro-1H-quinoxalin-2-yl)benzamide
El Houssine Mabrouk1 1Laboratory of Organic Chemistry, Faculty of Sciences DharElMehraz, University Sidi Mohamed Ben Abdellah, Fez, B.P.:1796-Fès Atlas, Morocco ABSTRACT The title compound, N-(3-Oxo-2,4-dihydro-1H-quinoxalin-2-yl)benzamide2, was synthesized in high yield, via N-alkylation reaction of methyl 2-azido-2-benzamidoacetate or methyl 2-bromo-2-benzamidoacetate with o-phenylenediaminein acetone, with the presence of diisopropylethylamine(DIEPA) as a base. The structure of the prepared compound was characterized by 1H, ... Read More »
Synthesis of methyl 2-benzamido-2-(5-(4-methoxyphenyl)tetrazol-1-yl)acetate and methyl 2-benzamido-2-(5-(4-methoxyphenyl)tetrazol-2-yl)acetate
El Houssine Mabrouk Laboratory of Organic Chemistry, Faculty of Sciences Dhar El Mehraz, University Sidi Mohamed Ben Abdellah, B.P. 1796, Fez, Morocco ABSTRACT Heterocyclic amino acids represent a well-known group of organic compounds also presenting biological activity. We developed an environmentally benign, efficient, and simple method for the Synthesis of new racemic α-tetrazolyl α-carboxylic aminoesters derivatives by nucleophilic substitution of ... Read More »
Spectroscopic Analysis by UV &FT-IR of Cassia obtusifolia Seed Ethanolic Extract and Phytochemical Screening
Shahin Aziza, Shahal Ahmedb, MD.Zahangir Alamb aSenior Scientific Officer, Chemical Research Division, BCSIR Laboratories, Dhaka-1000, Bangladesh Council of Scientific and Industrial Research, Dhaka, Bangladesh. bDepartment of Applied Chemistry and Chemical Engineering, Islamic University, Kushtia-7003, Bangladesh ABSTRACT Cassia obtusifolia is an important medicinal plant medicinal plant. The present work deals with phytochemical screening, UV and FT-IR spectroscopy of ethanolic extract of Cassia ... Read More »
A Novel RP-HPLC Method Development and Validation for the Estimation of Pyrimethamine in Bulk and its Pharmaceutical Formulation
U. Srinivasulu*1, N. Devanna2, A. Sandhya 3, B. Siva Sai Kiran3, S. Muneer3 1Associate Professor of Chemistry, SBSYM Degree College, Kurnool-518004, A.P., India 2Professor and Director, Department of Chemistry, JNTUA-Oil Technological and Pharmaceutical Research Institute, Ananthapuramu-515002, A.P., India. 3Department of Pharmaceutical Sciences, JNTUA-Oil Technological and Pharmaceutical Research Institute, Ananthapuramu-515002, A.P., India A B S T R A C T A simple, ... Read More »
Simultaneous Estimation of Moxonidine and Hydrochlorothiazide in Tablets by RP-HPLC
A. Thenmozhi, H. Mubeena*, N. Venkateshan Department of Pharmaceutical Analysis, Arulmigu Kalasalingam College of Pharmacy, Anand Nagar, Krishnankoil -626 190, Tamil Nadu. A B S T R A C T A simple, precise, specific sensitive and accurate reverse phase high performance liquid chromatographic (HPLC) method was developed for the determination of Moxonidine and Hydrochlorothiazide in tablet dosage form. The separation ... Read More »
