El Houssine Mabrouk and Abdelilah El Hallaoui Laboratory of Organic Chemistry, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, B.P. 1796, Fez, Morocco A B S T R A C T The title compound, Methyl 2-benzamido-2-(N-benzyl N-methylamino) acetate was synthesized in high yield by N-alkylation reaction between methyl α-bromo glycinate or methyl α-azido glycinate N-benzoylated and N-benzyl-N-methylamine ... Read More »
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Category Archives: Chemical Sciences and Chemical research
Formulation and Evaluation of Lamivudine Extentended Release Tablets
Dr. Srinivas Jagarlapudi, A. Ravi Kumar*, Panchumarthi Srinivas, M. Raveendra Babu, Alekhya Jagarlapudi Obvez Labs Pvt. Ltd. Plot No. 22 & 23, ALEAP Industrial Area, Pragathi Nagar, Hyderabad, Telangana. India- 500090. A B S T R A C T Now a day’s, Novel drug delivery system that plays a major role in the delivery of drug to specific site for ... Read More »
Analytical Method development for the Estimation of Related Substances by High performance Liquid Chromatographyfor the Rimonabent (RIM) drug
Dr. K. Mukkanti1, Dr. Srinivas Jagarlapudi2, Panchumarthi Srinivas*1, A. Ravi Kumar2, P. Ramyasree2 1Research Supervisor of Centre for Environment Institute of Science and Technology (Autonomous) Jawaharlal Nehru Technological University, Hyderabad, Telangana. India-500085. 2Obvez Labs Pvt. Ltd. Plot No. 22 & 23, ALEAP Industrial Area, Pragathi Nagar, Hyderabad, Telangana. India- 500090. A B S T R A C T The main aim ... Read More »
Analytical Method Development and Validation for Lamivudine and Zidovudine Combine Pharmaceutical Dosage Forms by RP-HPLC
Dr. Gampa Vijay Kumar*1, Dr. T. Rajesh2, C. Mounika3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2,3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T A new method was established for simultaneous estimation of Lamivudine and Zidovudine by RP-HPLC method. ... Read More »
Second order derivative spectrophotometry for simultaneous determination of Hg(II) and Ti(IV) using 3,4-dihydroxybenzaldehyde isonicotinoylhydrazone (DHBINH)
Dr. Srinivas Jagarlapudi*, Dr. V. Suryanarayana Rao, A. Ravi Kumar, Panchumarthi Srinivas, CH. Sunil Babu Obvez Labs Pvt. Ltd. Plot No. 22 & 23, ALEAP Industrial Area, Pragathi Nagar, Hyderabad, Telangana-500090, India. A B S T R A C T A second order derivative spectrophotometric method is developed for the simultaneous determination of mercury (II) and titanium (IV) using 3, ... Read More »
Analytical Method Development and Validation for the Estimation of Lacidipine in Bulk and Dosage Form by RP-HPLC
Dandu Girija1*, Akkimi Padma1, A. Thirupathireddy2, B. Venkateswara reddy3 1Assistant professor, Department of Pharmaceutical Analysis, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta(M), Prakasam(Dist) Andha pradesh pin -523370. 2Associate Professor, Department of Pharmaceutics, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta(M), Prakasam(Dist) Andha pradesh pin – 523370. 3Professor, Department of Pharmaceutics, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta (M), ... Read More »
Novel stability indicating RP-HPLC method for the determination of Ondansetron impurities in Ondansetron Injection
Dr. Srinivas Jagarlapudi*1, A. Ravi Kumar2, Panchumarthi Srinivas2, M. Raveendra Babu2, P. Ramyasree2 1Sri Krishnadevaraya University, Anatapuramu. Andhra Pradesh, India-515003. 2Sree Vidyanikethan College of Pharmacy, Sree Sainath Nagar, Tirupathi, A. Ranganpet, Andhra Pradesh-517102. A B S T R A C T The author developed a novel and unique RP-HPLC method for the determination of all the impurities of Ondansetron with ... Read More »
Analytical Method Development and Validation for Simultaneous Estimation of Pyrimethamine and Sulphadoxine in Pharmaceutical Dosage form by RP-HPLC
N. Kalpana Devi*1, Tirupathi Rao Velamala2, D.S.S.N.Neelima3 1,2 Teegala Krishna Reddy College of Pharmacy, Hyderabad, Telangana State 3Vikas Institite of Pharmaceutical Sciences, Rajahmundary A B S T R A C T A rapid and precise reverse phase high performance liquid chromatographic method has been developed for the validated of Sulphadoxine and Pyrimethamine, in its pure form as well as in ... Read More »
Formulation and Evaluation of Telmisartan Oral Films
S. Sai Vikas1*, M. Nirosha2, T. Pragna3, D. Shakeer4, L.Chandana5, D. Tarun6 Department of Pharmaceutics, JNTUA-Oil Technological & Pharmaceutical Research Institute, Ananthapuramu, AP, India. A B S T R A C T Fast disintegrating oral systems are designed to provide rapid onset of action within a minute without need of water, swallowing or chewing. Telmisartan is an anti-hypertensive agent which is ... Read More »
Experimental Evaluation of Anti-Epileptic Activity & In-vivo Antioxidant Activity of Aqueous Extract of Borassus Flabellifer Fruit Pulp in Albino Mice
N. Kalpana Devi1*, Chandrika Dontha2, D.S.S.N. Neelima3 1,2Teegala Krishna Reddy College of Pharmacy, Hyderabad, Telangana State 3Vikas Institite of Pharmaceutical Sciences, Rajahmundary A B S T R A C T The aqueous extract of Borassus flabellifer fruit pulp was tested for its anti-epileptic action at 200 mg/kg and 500 mg/kg using the standard drugs phenytoin (for MES) and valproic acid (for ... Read More »