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Syeda Jeelani Basri T*1, Dr. G.V. Subba Reddy2, Dr. K.N. Jayaveera3
1Department of Chemistry, Research Scholar JNTUA, Anantapur-515001, A.P, India.
2Department of Chemistry, Vice Principal, JNTU A College of Engineering Pulivendula, Pulivendula, A.P, India.
3Department of Chemistry, JNTUA, Anantapur-515001, A.P, India.
Abstract
Phytochemical analysis of Merremia turpethum plant samples revealed presence of Alkaloids, Amino acids, Carbohydrates, Glycosides, Anthraquinone, Saponin, Tannin and Triterpenoids.n-Hexane, Ethanol and Hydroalcohol solvent extracts of Merremia turpethum were tested for their antioxidant and cytotoxic activity. Positive antioxidant activity but with seasonal variation was found for all the extracts using TLC based standard qualitative 2,2 diphenyl-1-picrylhydrazys(DPPH) assay and hydrogen peroxide radical scavenging activity. However, a seasonal variation was observed in all the extracts. February and October were found to be favorable for the presence of antioxidant property. Ethanolic extract of Merremia turpethum showed maximum antioxidant bands(26.507) and promising antioxidant activity at par with the standard antioxidant ascorbic acid(IC50 19.933 microgram).The methanolic and hydroalcoholic extract showed moderate antioxidant activity. The potency of methanol extract of the plant showed rich antioxidant properties, so same was fractionated and a pure antioxidant fraction was isolated which showed good antioxidant activity.
Keywords: Antioxidant, Anthraquinone, Saponin, alkaloids, flavonoids, tannins, saponins, Merremia turpethum, DPPH, hydrogen peroxide radical scavenging activity.
