A Review on Meningitis

Sk. Meharunnisa, B. Kumar*, M. Gobinath
Department of Pharmacy Practice, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur (M), Nellore, Andhra Pradesh, India-524346

A B S T R A C T
Meningitis is an inflammatory disease of meninges membrane that covers the brain and spinal cord. Meningitis is more common in the neonatal period than any other time in life and is an important cause of morbidity and mortality globally. Despite the majority of the burden occurring in the developing world, the majority of the existing literature originates from wealthy countries. Mortality from neonatal meningitis in developing countries is estimated to be 40–58%, against 10% in developed countries. Important differences exist in the spectrum of pathogens isolated from cerebrospinal fluid cultures in developed versus developing countries. Bacterial Meningitis diagnosed by Staining methods. Group B streptococcus (GBS), Escherichia coli and Listeria monocytogenes as important organisms, we describe how in the developing world results have varied; particularly regarding GBS, other Gram negatives (excluding E. coli), Listeria and Gram-positive organisms. The choices of antibiotics are take into consideration of the treatment.
Keywords: Meningitis, Brain, spinal cord, antibiotics.etc.