A Non aqueous Titration Assay of Sodium in Sodium Carboxy methyl cellulose (CMC) as per USP/NF

Y. Yildiz*¹, G. Smith¹, J. Alfred^2
1Complete Analysis Research Laboratories, Analytical Research Department, 1259 Route 46, Suite 4C, Parsippany, NJ, 07054-USA
²EuTech Scientific Services, Inc.810 North Second Ave. Highland Park, NJ 08904-USA

A B S T R A C T
Cellulose is a major constituent of many foods of plant origin. Carboxy methyl cellulose sodium is the sodium salt of poly carboxy methyl ether of cellulose. In this study, sodium carboxy methyl-cellulose has been titrated with 0.1N perchloric acid VS and determining the percent sodium. CMC contains not less than 6.5% and not more not more than 9.5% of sodium (Na), calculated on the dried basis (1).
Keywords: Sodium carboxy methyl cellulose, Cellulose, Non aqueous Titration