A brief review on sublingual drug delivery system

Ajay Raj Yadav^*, Rahul Kumar Singh¹
Department of Pharmaceutics, Rajiv Academy for pharmacy, N.H. #2, Mathura Delhi Road, P.O. CHHATIKARA, Mathura, Uttar Pradesh 281001

A B S T R A C T
In Sublingual drug delivery system drug are placed under the tongue. Drugs are fastly absorbed by the oral mucosa which is directly reached in the systemic circulation.  The main advantage of the sublingual system is easily administrate by the patient and bypasses hepatic first pass metabolic process which gives better bioavailability, rapid onset of action, patient compliance, self-medicated. The absorption of drug through sublingual route is 3-10 times greater than that given oral route. In this review article highlight the sublingual dosage forms, factors affecting the sublingual absorption, advantages, evaluation method.
Keyword: Sublingual, advantage, dosage form, evaluation