Design Synthesis and Characterization of Novel Deuterated Heterocyclic Compounds as Antimycobacterials

Dhayalan.M^*, R. Vijay, Harsimran Kaur Kohli, Tejashwini .H
Department of Pharmaceutical Analysis, KLE College of Pharmacy, Bengaluru-560 010, Karnataka, India.

ABSTRACT
The Isoniazid- D was synthesized by using deuterium oxide and the percentage yield was calculated as 67%. The yield obtained was good. The deuterated Isoniazid was characterized by using IR Spectroscopy. The physiochemical properties were determined by Molinspiration Cheminformatics software. NMR Spectroscopic studies were carried out on a Bruker DRX Avance spectrometer equipped with a triple resonance inverse.
Keywords: Moringa oleifera, inhibitory activity, diabetes and hyperlipidemia