Formulation and Evaluation of Sustained Release Tablets of Valsartan

Charitha M*, Mahitha P, Prudhvi Raj V
Department of Pharmaceutics, Seven Hills College of Pharmacy, Tirupati.

A B S T R A C T
The present study was aimed to formulate and evaluate sustained release tablets of valsartan, which comes under BCS class iii, using HPMC as a polymer in different proportion by “Wet granulation method”. Compatibility among the formulation components was assessed by DSC analysis.  These prepared tablets were evaluated for various parameters like weight variation, hardness and friability, drug content, stability, swelling index and other parameters.
Keywords: Valsartan, sustained release, HPMC.