A Review on Anti-Cholesterol Drugs and Statins

ABOUT AUTHOR
Priyanka Patel*, Harnish Patel, Akshay Patel, Taher Patel
Managing Editor, IJPRBS, Gujarat.
Editor-In-Chief, IJPRBS, Gujarat.
L.B Rao Institute of Pharmaceutical Education & Research, B.D Rao Collage Campus, Khambhat
E-mail: editorijprbs@gmail.com

ABSTRACT
An in-depth report on the diagnosis, treatment, and prevention of unhealthy cholesterol levels.The statins (or HMG-CoA reductase inhibitors) along with other drugs, such as cholestyramine (Questran), comprise the class of hypolipidemic drugs. Hypolipidemic drugs are prescribed sometimes aggressively so to lower cholesterol levels in people with or at risk of cardiovascular disease and certain inflammatory diseases such as sarcoidosis. Statins are prescribed even though their full mechanisms of action remain unclear. One strong possibility is that statins exert their effects via the body’s nuclear receptors, which are intricately connected to innate immune function. Statins may have benefits other than just lowering your cholesterol. One promising benefit of statins appears to be their anti-inflammatory properties, which help stabilize the lining of blood vessels. This has potentially far-reaching effects, from the brain and heart to blood vessels and organs throughout the body. In the heart, stabilizing the blood vessel linings would make plaques less likely to rupture, thereby reducing the chance of a heart attack.
Key words: Hypercholesterolemia, LDL, HDL, Triglycerides