Antioxidant and Antimicrobial Activity of Grape Seed Extract

Ms. Sneha V & Dr. V. Judia Harriet Sumathy*
Postgraduate & Research Department of Biotechnology, Women’s Christian College, Chennai – 600 006.

A B S T R A C T
Recent studies have shown that procyanidins in grape seeds possess anti-inflammatory, anti-arthritic, anti-allergic and anti-cancer activities. It is also reported that it prevents heart disease and skin aging besides inhibiting carrageen in dextran-induced hindpawedema which stabilizes the capillary wall and improves visual performance in humans. The concentration of phenolic compounds in grapes depends on the variety of grapevine and is influenced by viticultural and environmental factors. The synthesis of flavonoid and non-flavonoid plant polyphenols such as stilbenes is increased in plant tissues following wounding or infection by pathogenic organisms. The present study is aimed at extracting red grapes seed with methanol and perform the Phytochemical tests using qualitative analysis. Furthermore Total Phenolic content by Quantitative analysis, Column Chromatography by GC-MS to confirm the secondary metabolites for seed, Antioxidant activity by DPPH, Hydrogen Peroxide and Total antioxidant capacity and Antibacterial activity for grape seed extract is also assessed.
Keywords: Grape seed, Procyanidins, Phytochemical Analysis, Antioxidant and Antimicrobial Property