Thursday , 21 November 2024

Synthesis and Antimicrobial Activity Evaluation of Poly ethylen imine (PEI) Dendrimer modified with 1,2,4-oxadiazole derivatives

Author Details
Maziar Mansouji Avval1*, V. Srinivasa Murthy 2, S.Shashikanth1
1Department of Studies in Chemistry, University of Mysore, Manasagangorti 570006, India.
2BNM Institute of technology, Bhanashankari, Bangalore, 560 076, India.

Abstract
Dendrimers have wide range of applications in industry, Pharmaceutical and medicine. Oxadiazole compounds also have many applications in Pharmaceutical and medicine. Modification of dendrimers which have many branches like –NH2 functional groups with heterocyclic derivatives make them capable to show variety properties. In this article, PEI-dend-4[N[(Ts)(5-(methyl)-3-aryl-1,2,4 oxadiazole) ]] 8a-g have been synthesized from PEI (Poly ethylene imine) dendrimer which modified with 1,2,4 oxadiazole derivatives and investigated their antimicrobial activities.
Keywords: Poly ethylene imine (PEI). Dendrimer. 1,2,4-Oxadiazole, Antimicrobial.

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