Pharmacological Evaluation of Antioxidant Activity of Methanolic Extract of Mucuna Pruriens Seeds.

C. Madhavi Latha*, SK. Salma Sulthana
Department of Pharmacology, Jagans College of Pharmacy, Jangalakandriga, Muthukur, Nellore -524346, A.P, India

A B S T R A C T
Antioxidant activity of methanolic extract of Mucuna pruriens L. (Fabaceae) seeds were evaluated in male Wister albino rats. The methanolic extract of Mucuna pruriens L.2000mg/kg (MEMP) was administered orally to different groups of rats for two times at an interval of 12 hours & continued for 30 days. MEMP suppressed the accumulation of lipid peroxidation in the plasma as well as maintained the activities of antioxidant enzymes such as superoxide dismutase (SOD) & catalase. The present investigation confirmed the antioxidant effect of the methanolic extract of Mucuna pruriens.
Keywords: Antioxidant enzymes, Mucuna pruriens L.