Past work done on Matrix Tablets: Journal based review

Teja Boda, Ramesh Naik M, Babu B, Hindustan Abdul Ahad*
Balaji College of Pharmacy, Anantapur, AP, India

A B S T R A C T
A wide range of drugs have been studied in the form of matrix tablets. Many polymers were tried in single, combination of two and more for sustaining the drug release from matrix type of dosage forms. An attempt has been made in gathering the information regarding which are the drugs and polymers have been tried in recent years. More than 100 articles published in journals were studied and the polymer combinations used were represented as pie diagrams. The study concludes that more than 64 % matrix tablets were prepared by using HPMC. The second polymer tried and succeeded was Eudragit. HPMC+PVP and xanthan gum + Guar gum combinations were tried. On the other hand HPMC, Eudragit, Xanthan gum and Guar gum combinations were used much in multiple polymer combinations.
Keywords: Matrix Tablets, HPMC, Eudragit, Xanthan gum, Guar gum