Oxidative Stress and Inflammation

Kamalakararao Konuku^1*, Krishna Chaitanya Karri¹, Patricia Ponce-Noyola², John Dogulas Palleti², Venugopal Reddy Bovilla³, S.B.Padal⁴, RajyalakshmiAmancherla⁵, Anjali jha⁶, Dr. M. Muthulingam⁷, Govinda Rao Duddukuri^1
1Department of Biochemistry, Institute of Science, GITAM University, Visakhapatnam, A.P, India.
²Department of Life Sciences, University of Guanajuato, Mexico.
³Department of Biochemistry, JSS Medical College, JSS University, Mysore.
⁴Department of Botany, Andhra University, Visakhapatnam, Andhra Pradesh, India.
⁵Director, Bio world research technologies, Hyderabad, Telangana, India.
⁶Department of Chemistry, Institute of Science, GITAM University, Visakhapatnam, Andhra Pradesh, India.
⁷Assistant Professor of Zoology, Faculty of Science, Annamalai University, Tamilnadu, India

A B S T R A C T
Oxidative stress is an imbalance between prooxidant and antioxidant system, it is associated with upregulation of reactive oxygen species and reactive nitrogen species, these reactive oxygen species causes radical induced inflammatory diseases and cancer. Many synthetic antioxidants are useful for curing radical induced inflammatory diseases, due to side effects of these drugs, ethanopharmacologists focus on development of plant derived antioxidants for formulation of safer and effective antioxidant drugs.
Keywords: Antioxidants, inflammation, reactive oxygen species, oxidative stress, superoxide dismutase, curcumin.