Novel Tactic in Designing Mouth Dissolving Atenolol tablets

Teja Boda¹*, Hindustan Abdul Ahad¹, Ishaq B Md¹, Ramesh Dhani^2
1PG Department of Pharmaceutics, Balaji College of Pharmacy, Ananthapuramu, Andhra Pradesh, India
²Dept. of Pharmaceutical Chemistry, Ratnam Institute of Pharmacy, SPSR Nellore, Andhra Pradesh, India-524346
APOTHEKE-2014, 8 Nov 2014, Organized by Balaji College of Pharmacy, Ananthapuramu, Andhra Pradesh, India

Abstract
Mouth dissolving drug delivery systems has faster onset of action, classiness, ease of admin, ease of engineering, easy to store and carrying. A different tactic has been made to develop mouth dissolving tablets of Atenolol by incorporating clove oil as flavor and local anesthetic on taste buds. Atenolol tablets were made by direct compression method. The prepared tablets were checked for Pre compression and post compression parameters and they were found to be satisfactory. The prepared tablets found to have better drug releasing characteristics, mouth feel and enhanced drug obtain ability with better patient acquiescence.
Keywords: Mouth dissolving, Atenolol tablets, direct compression, superdisintegrants, Clove oil.