Method Development and Validation of Etizolam in Tablet Formulation by Using UV Double Beam Spectrophotometer

V. Amaravathi*, Dr. P. Venkatesh, K. Sai Keerthi, K. Sudheer, M. Vijaya Lakshmi, N. Chaithanya, P. Priyanka, P. Vidhya
Jagan’s Institute of Pharmaceutical Sciences, Jangalakandriga (V), SPSR Nellore, A.P, India

ABSTRACT
The present work was aimed to develop and validate UV spectrophotometric method for the quantification of Etizolam in tablet formulation. Methanol used as a solvent. The absorption maxima were measured at 245 nm. This method shows linearity in the range of 5-30μg/ml with correlation coefficient was found to be 0.999. The proposed methods were found to be precise, reproducible and accurate and can be employed for routine quality control analysis of Etizolam in bulk drug as well as dosage forms.
Keywords: Etizolam, UV Spectrophotometry, Methanol.