In-vitro anticoagulant activity of marine brown algae species Padina tetrastromatica

Pandian*¹, K. Kathiresan²
Assistant Professor, Department of Pharmacy, Annamalai University, Annamalainagar

A B S T R A C T
The brown algae exhibit many health beneficial nutraceutical effects such as antioxidant, anti-allergic, anti-human immunodeficiency virus, anticancer and anticoagulant activities. To prevent abnormal bleeding and to maintain intravascular blood in a fluid state, in this study we aimed to evaluate the possible anticoagulant effect of marine algae extracts of Padina tetrastromatica. The algae was collected from different locations of Mandapam area, Tamilnadu, extracted with chloroform, methanol solvent the standard kit was purchased for the anticoagulant assay the APTT, PT, TT assay were performed and different concentration was used from 2mg/ml to 20mg/ml the result was tabulated and the methanol solvent possess more anticoagulant than chloroform as APTT value for 20mg/ml is 179sec, PT values is 54sec and TT values is 74 respectively.