Evaluation of the Antioxidant and Antimicrobial activity of the Myrica nagi Leaf extracts

Saritha Chandra*, Maredupalli Bharath, Maru Keerthi, Maruthi Vishnu Pooja, Talari Bhagya Lakshmi, Yesupaku Rakesh
Narayana Pharmacy College, Chintha Reddy Palem, Nellore, Andhra Pradesh, India

A B S T R A C T
Nutraceutical is a combination of two words nutrition and pharmaceutical which provides health and medical benefits, including the prevention and treatment of diseases. These are products derived from food sources that provide extra health benefits, in addition to the basic nutritional value found in foods. Products typically claim to prevent chronic diseases, improve health, delay the aging process, and increase life expectancy. All the samples tested using Nitric oxide radical inhibition method and ABTS method EEW extract exhibited potent activity with a IC50 value 140μg/m The main aim of the present study is to screen the antioxidant and anti-microbial activity of the leaf extract of Myrica naga with an objective of utilizing the extract as a neutraceuticals in future.   The result of the study confirms the antioxidant property of the leaf extract of Myrica naga by Nitric oxide radical inhibition activity method. l and 175μg/ml. EEW extract  exhibited moderate antioxidant activity under lipid peroxidation method. This result suggests that the selected herbal based anti-asthmatic constituents play a vital role in scavenging Nitric oxide which could prevent the bronchial inflammation in asthmatic patients. Because Nitric oxide is naturally formed in activated macrophages and endothelial cells and it is considered as an active agent in several pathologies based on inflammation. The extract also showed potent antioxidant activity under DPPH and Hydrogen peroxide method.
Keywords: Nutraceutical, Myrica nagi, Anti-microbial activity, Anti-oxidant activity