Evaluation of In-vitro and In–vivo Anti-oxidant Activity of Roots of Kandelia rheedei and Leaves of Euphoria lopogona

Guntheti Chiranjeevi¹, Yellu Narsimha Reddy*², Pabba Parameshwar^3
1Department of Pharmacology, Sree College of Pharmacy, Kammam, Telangana, India
²Department of Pharmacology, University College of Pharmaceutical Sciences, Kakatiya University, Warangal, Telangana, India
³Department of Pharmacology, Jyothishmathi Institute of Pharmaceutical Science, Ramakrishna colony, Karimnagar, Telangana, India

A B S T R A C T
The literature survey   shown Mangrove and Cactus Plants were also have the tremendous important in the treatment of the disease.  Roots of Kandelia rheedei (Rhizophoraceae) and Leaves of Euphorbia lopogona (Euphorbiaceae) were selected for the evaluation of anti-oxidant activity. Phytochemical screening revels that the plants having the flavonoids, tannins, proteins and phenols.  From the above information plants shows anti-oxidant, hepatoprotective, antidiabetic and anti hyperlipidamic activity. DPPH method, Lipid-peroxidation method , the ethyl acetate fraction of both plant extracts shown  significant free radical scavenging activity,  the  IC₅₀ value were decreased when concentrations of fractions increased this values indicates the potency of the   herbs showing the anti-oxidant activity.
Keywords: Anti-oxidant activity, Kandelia rheedei, Euphorbia lopogona, DPPH method, Lipid peroxidation method.