Antinociceptive Activity of Symphytum Officinale Linn. Root on Swiss Albino Mice

D. Yashwanth Kumar*¹, D.S.S.N. Neelima¹, Pradeep Kumar Choda², Namani Srilatha^2
1Scientific and Applied Research Center, Hyderabad, Telangana, India
²Department of Pharmacology, Teegala Krishna Reddy College of Pharmacy, Hyderabad, Telangana, India

A B S T R A C T
Methanolic extract of the root of Symphytum officinale Linn was investigated for the analgesic activity. Experiments were carried out with this extract for their central antinociceptive potential on eddy’s hot plate method in mice. In this model, methanolic extract showed significant increase in reaction time at doses of extract 200mg and 400mg/kg b.wt when compared to control.
Keywords: Symphytum officinale Linn, Anti nociceptive potential, Eddy’s hot plate method