Anti-inflammatory Activity of Ethanolic and Aqueous extracts of Toxocarpus beddomei Gamble

J. Karthi*1, M. Purushothaman2
1Sun Rise University, Alwar, Rajasthan – 301030, India
2Scient Institute of Pharmacy, Ibrahimpatnam, Ranga Reddy (Dt), Hyderabad, Talangana-501 506, India.

A B S T R A C T
In this study anti-inflammatory activity of ethanolic and aqueous extracts of Toxocarpus beddomei Gamble belonging to family apocynaceae were studied in. Preliminary phytochemical screening revealed the presence of various vital components. The ethanol & aqueous extracts of Toxocarpus beddomei Gamble was found to be effective in a dose dependent manner against Carrageenan induced rat paw oedema and cotton pellet induced granuloma on experimental rats at the dose of 200 mg/kg and 400 mg/kg body weight, The extract produced a significant decrease in the inflammation in terms of reduction in the paw oedema and granuloma in albino rats. At the same dose, the extract showed significant anti-inflammatory activity comparable to that of the standard drug Indomethacin.
Keywords: Toxocarpus beddomei Gamble, Anti-inflammatory, Apocynaceae, Paw oedema, granuloma